Literature DB >> 30988569

Does Transfusion of Blood and Blood Products Increase the Length of Stay in Hospital?

Ayten Saraçoğlu1, Mehmet Ezelsoy2, Kemal Tolga Saraçoğlu3.   

Abstract

We aimed to analyze the use of blood products in cardiac surgery and to investigate its effect on clinical outcomes. Perioperative transfusion requirement, survival and complication rates and the duration of hospitalization were noted. Patients were divided into two groups considering the duration of hospital and intensive care unit (ICU) stay. The cardiopulmonary bypass time and the cross clamp time, and the amount of used cryoprecipitate, fresh frozen plasma, platelet, red blood cell and the bleeding amount were significantly higher in groups that stayed at the hospital for > 7 days and at the ICU for > 2 days (p > 0.05). In the univariate model, to predict the patients who might stay at the hospital for more than 1 week and who might stay at the ICU for more than 3 days, we considered the significant efficacy of postoperative blood transfusion, bleeding amount, and the cardiopulmonary bypass time (p < 0.05). In the reduced multivariate model, however, we analyzed the significant-independent efficacy of the postoperative fresh frozen plasma use to determine the patients who would stay at the hospital for more than 1 week and who would stay at the ICU for more than 3 days (p < 0.05). We have concluded that increased use of blood products was associated with the cross clamp and cardiopulmonary bypass time and prolonged duration of hospital and ICU stays. In open cardiac surgeries, the use of blood products due to bleeding was identified as a predictor for staying longer than 3 days at the ICU and longer than 7 days at the hospital.

Entities:  

Keywords:  Blood transfusion; Cardiac surgery; Complication; Length of hospital stay

Year:  2018        PMID: 30988569      PMCID: PMC6439024          DOI: 10.1007/s12288-018-1039-5

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  20 in total

1.  Transfusion of 1 and 2 units of red blood cells is associated with increased morbidity and mortality.

Authors:  Gaetano Paone; Donald S Likosky; Robert Brewer; Patricia F Theurer; Gail F Bell; Chad M Cogan; Richard L Prager
Journal:  Ann Thorac Surg       Date:  2013-10-03       Impact factor: 4.330

2.  Guidelines for transfusion support in patients undergoing coronary artery bypass grafting. Transfusion Practices Committee of the American Association of Blood Banks.

Authors:  L T Goodnough; M F Johnston; G Ramsey; M H Sayers; R S Eisenstadt; K C Anderson; R C Rutman; L E Silberstein
Journal:  Ann Thorac Surg       Date:  1990-10       Impact factor: 4.330

3.  Blood transfusion after pediatric cardiac surgery is associated with prolonged hospital stay.

Authors:  Joshua W Salvin; Mark A Scheurer; Peter C Laussen; David Wypij; Angelo Polito; Emile A Bacha; Frank A Pigula; Francis X McGowan; John M Costello; Ravi R Thiagarajan
Journal:  Ann Thorac Surg       Date:  2011-01       Impact factor: 4.330

4.  Modifiable Factors Leading to Increased Length of Stay after Carotid Endarterectomy.

Authors:  James H Mehaffey; Damien J LaPar; Margret C Tracci; Kenneth J Cherry; John A Kern; Irving Kron; Gilbert R Upchurch
Journal:  Ann Vasc Surg       Date:  2016-08-20       Impact factor: 1.466

5.  Long-term survival and quality of life in cardiac surgical patients with prolonged intensive care unit length of stay.

Authors:  Mathew R Williams; Rachel B Wellner; Elizabeth A Hartnett; Barbara Thornton; Minoo N Kavarana; Robert Mahapatra; Mehmet C Oz; Robert Sladen
Journal:  Ann Thorac Surg       Date:  2002-05       Impact factor: 4.330

6.  Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.

Authors:  Gavin J Murphy; Barnaby C Reeves; Chris A Rogers; Syed I A Rizvi; Lucy Culliford; Gianni D Angelini
Journal:  Circulation       Date:  2007-11-12       Impact factor: 29.690

7.  Is transfusion associated with graft occlusion after cardiac operations?

Authors:  Milo Engoren; Thomas A Schwann; Elizabeth Jewell; Sean Neill; Patrick Benedict; Donald S Likosky; Robert H Habib
Journal:  Ann Thorac Surg       Date:  2014-12-12       Impact factor: 4.330

Review 8.  The efficacy of an intraoperative cell saver during cardiac surgery: a meta-analysis of randomized trials.

Authors:  Guyan Wang; Daniel Bainbridge; Janet Martin; Davy Cheng
Journal:  Anesth Analg       Date:  2009-08       Impact factor: 5.108

9.  The cardiotomy trial: a randomized, double-blind study to assess the effect of processing of shed blood during cardiopulmonary bypass on transfusion and neurocognitive function.

Authors:  Fraser D Rubens; Munir Boodhwani; Thierry Mesana; Denise Wozny; George Wells; Howard J Nathan
Journal:  Circulation       Date:  2007-09-11       Impact factor: 29.690

Review 10.  Indications for red blood cell transfusion in cardiac surgery: a systematic review and meta-analysis.

Authors:  Nishith N Patel; Vassilios S Avlonitis; Hayley E Jones; Barnaby C Reeves; Jonathan A C Sterne; Gavin J Murphy
Journal:  Lancet Haematol       Date:  2015-11-17       Impact factor: 18.959

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  1 in total

1.  Risk factors for prolonged intensive care unit stays in patients after cardiac surgery with cardiopulmonary bypass: A retrospective observational study.

Authors:  Xueying Zhang; Wenxia Zhang; Hongyu Lou; Chuqing Luo; Qianqian Du; Ya Meng; Xiaoyu Wu; Meifen Zhang
Journal:  Int J Nurs Sci       Date:  2021-09-07
  1 in total

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