Literature DB >> 3098714

A single dominant susceptible gene determines spontaneous development of thymoma in BUF/Mna rat.

M Matsuyama, C Yamada, H Hiai.   

Abstract

Rats of the BUF/Mna strain developed spontaneous epithelial thymomas morphologically indistinguishable from human homologues at virtually 100% incidence. Segregation of thymoma development among crosses between BUF/Mna and ACI/NMs, which has 0% thymoma incidence, indicated that thymoma susceptibility was determined principally by a single autosomal dominant gene Tbm-1 (thymoma in BUF/Mna rats). In these crosses, another autosomal dominant or semidominant gene(s) contributed by ACI/NMs parents moderately reduced the thymoma incidence.

Entities:  

Mesh：

Year:  1986        PMID： 3098714

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  12 in total

1.  Thymic nurse cells (TNC) in spontaneous thymoma BUF/Mna rats as a model to study their roles in T-cell development.

Authors:  T Ezaki; K Matsuno; M Kotani
Journal:  Immunology       Date:  1991-06       Impact factor: 7.397

2.  Establishment of functional epithelial cell lines from a rat thymoma and a rat thymus.

Authors:  A Masuda; K Ohtsuka; M Matsuyama
Journal:  In Vitro Cell Dev Biol       Date:  1990-07

3.  The effect of thymectomy on the development of nephropathy in spontaneous thymoma rats of the BUF/Mna strain.

Authors:  T Nakamura; M Matsuyama; A Kojima; T Ogiu; A Kubota; Y Suzuki; M Arakawa; F Shimizu
Journal:  Clin Exp Immunol       Date:  1988-02       Impact factor: 4.330

4.  Cervical thymuses exist, but no cervical thymomas develop in thoracic thymoma-prone BUF rats.

Authors:  Tetsuji Yamada; Mutsushi Matsuyama; Takamasa Yanagida; Kazuo Kato; Seiji Sugiura; Makoto Kuroda
Journal:  Int J Exp Pathol       Date:  2011-02-12       Impact factor: 1.925

5.  Mapping of two genetic loci, Ten-1 and Ten-2, associated with thymus enlargement in BUF/Mna rats.

Authors:  Y Murakumo; M Takahashi; N Sharma; A Arakawa; M Saito; H Amo; M Matsuyama
Journal:  Mamm Genome       Date:  1996-07       Impact factor: 2.957

6.  Extrarenal effects on the pathogenesis and relapse of idiopathic nephrotic syndrome in Buffalo/Mna rats.

Authors:  Ludmilla Le Berre; Yann Godfrin; Eberhard Günther; Françoise Buzelin; Sabine Perretto; Helga Smit; Dontscho Kerjaschki; Claire Usal; Cristina Cuturi; Jean-Paul Soulillou; Jacques Dantal
Journal:  J Clin Invest       Date:  2002-02       Impact factor: 14.808

7.  Establishment of thymoma-prone congenic rat strain, ACI.BUF/Mna-Tsr1/Tsr1.

Authors:  Mutsushi Matsuyama; Kazuo Kato; Kyoko Higo-Moriguchi; Tetsuji Yamada; Takashi Kuramoto; Makoto Kuroda
Journal:  J Cancer Res Clin Oncol       Date:  2008-01-22       Impact factor: 4.553

8.  Oestrogen retards the development of spontaneous thymomas in BUF/Mna rats.

Authors:  T Ezaki; H Fujii; K Matsuno; R Kawatsu; M Kotani
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

9.  An intrinsic thymic epithelial abnormality is responsible for the spontaneous development of predominantly lymphocytic thymomas in BUF/Mna rats.

Authors:  O Taguchi; K Kontani; H Ikeda; M Matsuyama
Journal:  Jpn J Cancer Res       Date:  1992-11

10.  Nodular development of spontaneous epithelial thymoma in (ACI/NMs x BUF/Mna)F1 rats.

Authors:  M Matsuyama; T Matsuyama; T Ogiu; A Kojima
Journal:  Jpn J Cancer Res       Date:  1988-09
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.