| Literature DB >> 3098685 |
R A Cox, L A Britt, R A Michael.
Abstract
Detection of antibody to Coccidioides immitis F antigen is of proved value in the diagnosis of coccidioidomycosis. This antibody is demonstrable by use of an immunodiffusion assay with reference coccidioidin antigen and antiserum to C. immitis. Using a combination of lectin affinity and immunoaffinity chromatography, we isolated the F antigen from coccidioidin and prepared monospecific antibody to the purified antigen. The availability of these reagents will enable the development of a sensitive and specific assay for detecting serologic reactivity to this antigen.Entities:
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Year: 1987 PMID: 3098685 PMCID: PMC260307 DOI: 10.1128/iai.55.1.227-232.1987
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441