| Literature DB >> 30985475 |
Yuntian Guan1,2, Joshua C Drake2, Zhen Yan1,2,3,4.
Abstract
Regular exercise enhances mitochondrial function by promoting healthy mitochondrial remodeling, but the underlying mechanisms are not thoroughly understood. An emerging hypothesis suggests that, in addition to anabolic events such as mitochondria biogenesis, the selective degradation of dysfunctional mitochondria (i.e., mitophagy) also is a key component of exercise-mediated adaptations in striated muscle, which eventually leads to better mitochondrial functions.Entities:
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Year: 2019 PMID: 30985475 PMCID: PMC6579614 DOI: 10.1249/JES.0000000000000192
Source DB: PubMed Journal: Exerc Sport Sci Rev ISSN: 0091-6331 Impact factor: 6.230