Literature DB >> 3098388

The origin of osteoclasts: an immunohistochemical study on macrophages and osteoclasts in embryonic rat bone.

T Sminia, C D Dijkstra.   

Abstract

The origin of osteoclasts was studied in embryonic rat bone primordia using a set of monoclonal antibodies (ED1, ED2, and ED3) that exclusively recognize monocytes and macrophage. ED1 recognizes monocytes and macrophages. Mononuclear phagocytes which were ED1 positive were found in the perichondrium/periosteum of developing bone. These cells started to infiltrate the primordia when the cartilage became hypertrophic. During bone formation, multinucleated ED1-positive cells with the morphological characteristics of osteoclasts were found in the developing bone marrow cavity and against the bone collar. The present findings support the notion that osteoclasts arise by fusion of mononuclear phagocytes derived from blood monocytes.

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Year:  1986        PMID： 3098388     DOI： 10.1007/bf02555216

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  10 in total

Review 1.  The pathobiology of the osteoclast.

Authors:  T J Chambers
Journal:  J Clin Pathol       Date:  1985-03       Impact factor: 3.411

2.  The development relationship between osteocytes and osteoclasts: a study using the quail-chick nuclear marker in endochondral ossification.

Authors:  F V Jotereau; N M Le Douarin
Journal:  Dev Biol       Date:  1978-04       Impact factor: 3.582

3.  On the origin of the osteoclast: the cell surface phenotype of rodent osteoclasts.

Authors:  M A Horton; E F Rimmer; A Moore; T J Chambers
Journal:  Calcif Tissue Int       Date:  1985-01       Impact factor: 4.333

4.  The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3.

Authors:  C D Dijkstra; E A Döpp; P Joling; G Kraal
Journal:  Immunology       Date:  1985-03       Impact factor: 7.397

5.  The role of mesenchyme in embryonic long bones as early deposition site for osteoclast progenitor cells.

Authors:  C W Thesingh; E H Burger
Journal:  Dev Biol       Date:  1983-02       Impact factor: 3.582

Review 6.  The origin of osteoclasts: evidence, clinical implications and investigative challenges of an extra-skeletal source.

Authors:  S C Marks
Journal:  J Oral Pathol       Date:  1983-08

Review 7.  The origin of osteoclasts.

Authors:  J F Loutit; N W Nisbet
Journal:  Immunobiology       Date:  1982-04       Impact factor: 3.144

8.  Cell surface antigens on osteoclasts and related cells in the quail studied with monoclonal antibodies.

Authors:  P J Nijweide; T Vrijheid-Lammers; R J Mulder; J Blok
Journal:  Histochemistry       Date:  1985

9.  The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages of bone and associated connective tissue.

Authors:  D A Hume; J F Loutit; S Gordon
Journal:  J Cell Sci       Date:  1984-03       Impact factor: 5.285

10.  In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes.

Authors:  E H Burger; J W Van der Meer; J S van de Gevel; J C Gribnau; G W Thesingh; R van Furth
Journal:  J Exp Med       Date:  1982-12-01       Impact factor: 14.307
  10 in total
  23 in total

1.  Osteoblastic meningiomas: clinico-pathological and immunohistochemical features of an uncommon variant.

Authors:  V Barresi; M Caffo; A Ieni; C Alafaci; G Tuccari
Journal:  J Neurooncol       Date:  2011-04-22       Impact factor: 4.130

2.  Different tartrate sensitivity and pH optimum for two isoenzymes of acid phosphatase in osteoclasts. An electron-microscopic enzyme-cytochemical study.

Authors:  T Akisaka; G P Subita; H Kawaguchi; Y Shigenaga
Journal:  Cell Tissue Res       Date:  1989-01       Impact factor: 5.249

3.  Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function.

Authors:  N A Athanasou; J Quinn
Journal:  J Clin Pathol       Date:  1990-12       Impact factor: 3.411

4.  A quantitative cytochemical investigation of osteoclasts and multinucleate giant cells.

Authors:  M H Zheng; J M Papadimitriou; G C Nicholson
Journal:  Histochem J       Date:  1991-04

Review 5.  Osteoimmunology: interactions of the bone and immune system.

Authors:  Joseph Lorenzo; Mark Horowitz; Yongwon Choi
Journal:  Endocr Rev       Date:  2008-05-01       Impact factor: 19.871

6.  Osteoclasts and a small population of peripheral blood cells share common surface antigens.

Authors:  T A Hentunen; J Tuukkanen; H K Väänänen
Journal:  Calcif Tissue Int       Date:  1990-07       Impact factor: 4.333

7.  Peri-tunnel bone loss: does it affect early tendon graft to bone tunnel healing after ACL reconstruction?

Authors:  Pauline Po Yee Lui; Yuk Wa Lee; Tsui Yu Mok; Yau Chuk Cheuk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-03       Impact factor: 4.342

8.  Induction of monocyte chemotaxis in devascularized rabbit bone.

Authors:  M R Sarkar; B A Rahn; U Pfister; H U Keller; S M Perren
Journal:  Arch Orthop Trauma Surg       Date:  1990       Impact factor: 3.067

9.  A monoclonal antibody (anti-L-35) which reacts with human osteoclasts and cells of the mononuclear phagocyte system.

Authors:  N A Athanasou; P A Hall; A J d'Ardenne; J Quinn; J O McGee
Journal:  Br J Exp Pathol       Date:  1988-04

10.  Zoledronate inhibits ischemia-induced neovascularization by impairing the mobilization and function of endothelial progenitor cells.

Authors:  Shih-Hung Tsai; Po-Hsun Huang; Wei-Chou Chang; Hsiao-Ya Tsai; Chih-Pei Lin; Hsin-Bang Leu; Tao-Cheng Wu; Jaw-Wen Chen; Shing-Jong Lin
Journal:  PLoS One       Date:  2012-07-25       Impact factor: 3.240
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