Literature DB >> 3098308

Accumulation of dinucleoside polyphosphates in Saccharomyces cerevisiae under stress conditions. High levels are associated with cell death.

M Baltzinger, J P Ebel, P Remy.   

Abstract

Adenosine tetraphosphonucleosides (Ap4X) were measured in Saccharomyces cerevisiae by a coupled phosphodiesterase-luciferase assay. After exposure of the cells to cadmium or to hyperthermic treatment (46 degrees C) a marked increase of the cellular pool from 0.08 microM (base level) to 4 microM or higher was observed. The accumulation of Ap4X to high levels is associated with irreversible processes leading to cell death.

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Year:  1986        PMID： 3098308     DOI： 10.1016/s0300-9084(86)80069-4

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  14 in total

1.  Isolation, characterization, and inactivation of the APA1 gene encoding yeast diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase.

Authors:  P Plateau; M Fromant; J M Schmitter; J M Buhler; S Blanquet
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490

2.  Synthesis and resistance to enzymic hydrolysis of stereochemically-defined phosphonate and thiophosphate analogues of P1,P4-bis(5'-adenosyl) tetraphosphate.

Authors:  G M Blackburn; G E Taylor; G R Thatcher; M Prescott; A G McLennan
Journal:  Nucleic Acids Res       Date:  1987-09-11       Impact factor: 16.971

3.  Disruption and overexpression of the Schizosaccharomyces pombe aph1 gene and the effects on intracellular diadenosine 5',5'''-P1, P4-tetraphosphate (Ap4A), ATP and ADP concentrations.

Authors:  S W Ingram; L D Barnes
Journal:  Biochem J       Date:  2000-09-15       Impact factor: 3.857

4.  Variation in intracellular P1P4-bis(5'-adenosyl) tetraphosphate (Ap4A) in virus-infected cells.

Authors:  D J Johnston; C A Hart; A G McLennan
Journal:  Biochem J       Date:  1990-06-15       Impact factor: 3.857

5.  Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis.

Authors:  Pietro I Giammarinaro; Megan K M Young; Wieland Steinchen; Christopher-Nils Mais; Georg Hochberg; Jin Yang; David M Stevenson; Daniel Amador-Noguez; Anja Paulus; Jue D Wang; Gert Bange
Journal:  Nat Microbiol       Date:  2022-08-11       Impact factor: 30.964

6.  4-Coumarate:coenzyme A ligase has the catalytic capacity to synthesize and reuse various (di)adenosine polyphosphates.

Authors:  Małgorzata Pietrowska-Borek; Hans-Peter Stuible; Erich Kombrink; Andrzej Guranowski
Journal:  Plant Physiol       Date:  2003-03       Impact factor: 8.340

7.  Cell cycle variations of dinucleoside polyphosphates in synchronized cultures of mammalian cells.

Authors:  G Orfanoudakis; M Baltzinger; D Meyer; N Befort; J P Ebel; J J Befort; P Remy
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

8.  Changes in diadenosine tetraphosphate levels in Physarum polycephalum with different oxygen concentrations.

Authors:  P N Garrison; S A Mathis; L D Barnes
Journal:  J Bacteriol       Date:  1989-03       Impact factor: 3.490

9.  Diadenosine polyphosphates (Ap3A and Ap4A) behave as alarmones triggering the synthesis of enzymes of the phenylpropanoid pathway in Arabidopsis thaliana.

Authors:  Małgorzata Pietrowska-Borek; Katarzyna Nuc; Małgorzata Zielezińska; Andrzej Guranowski
Journal:  FEBS Open Bio       Date:  2011-10-19       Impact factor: 2.693

10.  Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae.

Authors:  Marta Rubio-Texeira; James M Varnum; Pawel Bieganowski; Charles Brenner
Journal:  BMC Mol Biol       Date:  2002-05-20       Impact factor: 2.946
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