Literature DB >> 309827

Role of catechol structure in the inhibitory effects of D-isomers of amino acids on the decarboxylation of L-5-hydroxytryptophan.

T Shikimi, C Inagaki, S Takaori.   

Abstract

D-3,4-dihydroxyphenylalanine, D-threo-3,4-dihydroxyphenylserine and pyrocatechol competitively inhibited aromatic L-amino acid decarboxylase, whereas no inhibition occurred with l-norepinephrine, l-epinephrine, dopamine or some other amino acids without catechol side chains.

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Year:  1978        PMID: 309827     DOI: 10.1007/bf01922950

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  10 in total

1.  Studies on inhibition of L-DOPA decarboxylase in vitro and in vivo.

Authors:  W G CLARK
Journal:  Pharmacol Rev       Date:  1959-06       Impact factor: 25.468

2.  The decarboxylation of amino acids related to tyrosine and their awakening action in reserpine-treated mice.

Authors:  H BLASCHKO; T L CHRUSCIEL
Journal:  J Physiol       Date:  1960-05       Impact factor: 5.182

3.  Aromatic L-amino acid decarboxylase.

Authors:  W LOVENBERG; H WEISSBACH; S UDENFRIEND
Journal:  J Biol Chem       Date:  1962-01       Impact factor: 5.157

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Inhibitory effects of D-isomers of aromatic amino acids on the decarboxylation of L-5-hydroxytryptophan.

Authors:  T Shikimi; C Inagaki
Journal:  Jpn J Pharmacol       Date:  1978-02

6.  Rat brain L-3,4-dihydroxyphenylalanine and L-5-hydroxytryptophan decarboxylase activities: differential effect of 6-hydroxydopamine.

Authors:  K L Sims; F E Bloom
Journal:  Brain Res       Date:  1973-01-15       Impact factor: 3.252

7.  Activities of 3,4-dihydroxy-L-phenylalanine and 5-hydroxy-L-tryptophan decarboxylases in rat brain: assay characteristics and distribution.

Authors:  K L Sims; G A Davis; F E Bloom
Journal:  J Neurochem       Date:  1973-02       Impact factor: 5.372

8.  On the identity of DOPA decarboxylase and 5-hydroxytryptophan decarboxylase (immunological titration-aromatic L-amino acid decarboxylase-serotonin-dopamine-norepinephrine).

Authors:  J G Christenson; W Dairman; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205

9.  Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney.

Authors:  J G Christenson; W Dairman; S Udenfriend
Journal:  Arch Biochem Biophys       Date:  1970-11       Impact factor: 4.013

10.  Inhibitory effect of (+)threo-3,4-dihydroxy-phenylserine (DOPS) on decarboxylation of (-)threo-dops.

Authors:  C Inagaki; H Fujiwara; C Tanaka
Journal:  Jpn J Pharmacol       Date:  1976-06
  10 in total

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