Literature DB >> 30980905

Expanding the activity spectrum of antiviral agents.

Aleksandr Ianevski1, Petter I Andersen1, Andres Merits2, Magnar Bjørås3, Denis Kainov4.   

Abstract

Broad-spectrum antivirals (BSAs) are agents that inhibit replication of several human viruses. Here, we review 108 approved, investigational, and experimental BSAs, for which safety profiles in humans are available. The most effective and tolerable BSAs could reinforce the arsenal of available antiviral therapeutics pending the results of further pre-clinical and clinical studies.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID： 30980905     DOI： 10.1016/j.drudis.2019.04.006

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  12 in total

1.  Safe-in-Man Broad Spectrum Antiviral Agents.

Authors:  Rouan Yao; Aleksandr Ianevski; Denis Kainov
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Nodosome Inhibition as a Novel Broad-Spectrum Antiviral Strategy against Arboviruses, Enteroviruses, and SARS-CoV-2.

Authors:  Daniel Limonta; Lovely Dyna-Dagman; William Branton; Valeria Mancinelli; Tadashi Makio; Richard W Wozniak; Christopher Power; Tom C Hobman
Journal:  Antimicrob Agents Chemother       Date:  2021-07-16       Impact factor: 5.191

3.  Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine.

Authors:  Petter I Andersen; Klara Krpina; Aleksandr Ianevski; Nastassia Shtaida; Eunji Jo; Jaewon Yang; Sandra Koit; Tanel Tenson; Veijo Hukkanen; Marit W Anthonsen; Magnar Bjoras; Magnus Evander; Marc P Windisch; Eva Zusinaite; Denis E Kainov
Journal:  Viruses       Date:  2019-10-18       Impact factor: 5.048

Review 4.  Selected nucleos(t)ide-based prescribed drugs and their multi-target activity.

Authors:  Gabriela Pastuch-Gawołek; Danuta Gillner; Ewelina Król; Krzysztof Walczak; Ilona Wandzik
Journal:  Eur J Pharmacol       Date:  2019-10-18       Impact factor: 4.432

Review 5.  Medicinal plants: Treasure for antiviral drug discovery.

Authors:  Sofi Imtiyaz Ali; Wajid Mohammad Sheikh; Muzafar Ahmad Rather; Venugopalan Venkatesalu; Showkeen Muzamil Bashir; Showkat Ul Nabi
Journal:  Phytother Res       Date:  2021-02-16       Impact factor: 6.388

6.  In silico binding analysis of lutein and rosmarinic acid against envelope domain III protein of dengue virus.

Authors:  Ritesh Panchal; Sanket Bapat; Sandeepan Mukherjee; Abhay Chowdhary
Journal:  Indian J Pharmacol       Date:  2021 Nov-Dec       Impact factor: 1.200

7.  Potential Antiviral Options against SARS-CoV-2 Infection.

Authors:  Aleksandr Ianevski; Rouan Yao; Mona Høysæter Fenstad; Svetlana Biza; Eva Zusinaite; Tuuli Reisberg; Hilde Lysvand; Kirsti Løseth; Veslemøy Malm Landsem; Janne Fossum Malmring; Valentyn Oksenych; Sten Even Erlandsen; Per Arne Aas; Lars Hagen; Caroline H Pettersen; Tanel Tenson; Jan Egil Afset; Svein Arne Nordbø; Magnar Bjørås; Denis E Kainov
Journal:  Viruses       Date:  2020-06-13       Impact factor: 5.048

Review 8.  Discovery and development of safe-in-man broad-spectrum antiviral agents.

Authors:  Petter I Andersen; Aleksandr Ianevski; Hilde Lysvand; Astra Vitkauskiene; Valentyn Oksenych; Magnar Bjørås; Kaidi Telling; Irja Lutsar; Uga Dumpis; Yasuhiko Irie; Tanel Tenson; Anu Kantele; Denis E Kainov
Journal:  Int J Infect Dis       Date:  2020-02-17       Impact factor: 3.623

9.  Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.

Authors:  Rui Xiong; Leike Zhang; Shiliang Li; Yuan Sun; Minyi Ding; Yong Wang; Yongliang Zhao; Yan Wu; Weijuan Shang; Xiaming Jiang; Jiwei Shan; Zihao Shen; Yi Tong; Liuxin Xu; Yu Chen; Yingle Liu; Gang Zou; Dimitri Lavillete; Zhenjiang Zhao; Rui Wang; Lili Zhu; Gengfu Xiao; Ke Lan; Honglin Li; Ke Xu
Journal:  Protein Cell       Date:  2020-08-04       Impact factor: 14.870

Review 10.  A roadmap to engineering antiviral natural products synthesis in microbes.

Authors:  Jingbo Ma; Yang Gu; Peng Xu
Journal:  Curr Opin Biotechnol       Date:  2020-08-11       Impact factor: 9.740
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