OBJECTIVE: To estimate the cumulative incidence of arthritis-induced orofacial symptoms, dysfunction, and dentofacial deformities in growing individuals with juvenile idiopathic arthritis (JIA) in a 36-month regional cohort study and to identify predictors for the development of arthritis-induced dentofacial deformities. METHODS: Data were retrieved from the Aarhus JIA temporomandibular joint (TMJ) cohort register, which contains standardized, longitudinal, observational data regarding orofacial conditions in patients with JIA (n = 1,040). This regional cohort represents the majority of all subjects with JIA from the western part of Denmark between 1990 and 2016, regardless of TMJ arthritis status. Cumulative incidences of orofacial conditions were reported using Kaplan-Meier methods, and predictors for dentofacial deformity were identified using Cox proportional hazards analysis. RESULTS: Follow-up data from 351 subjects for 36 months were included in this study. Median age at first clinical examination was 6.6 years (interquartile range 4.8-9.9 years). Orofacial symptoms and dysfunctions were common findings at 36 months after the first clinical examination and 5 years after JIA onset, with a cumulative incidence of 38% and 53%, respectively. Dentofacial deformities were found in 35% of subjects at the 36-month follow-up and were significantly associated with the presence of orofacial dysfunction. CONCLUSION: Orofacial conditions were frequently observed in individuals with JIA and were represented in all JIA subcategories in this regional study. One-third of subjects had arthritis-induced dentofacial deformities that required orthopedic appliance treatment at the 36-month follow-up.
OBJECTIVE: To estimate the cumulative incidence of arthritis-induced orofacial symptoms, dysfunction, and dentofacial deformities in growing individuals with juvenile idiopathic arthritis (JIA) in a 36-month regional cohort study and to identify predictors for the development of arthritis-induced dentofacial deformities. METHODS: Data were retrieved from the Aarhus JIA temporomandibular joint (TMJ) cohort register, which contains standardized, longitudinal, observational data regarding orofacial conditions in patients with JIA (n = 1,040). This regional cohort represents the majority of all subjects with JIA from the western part of Denmark between 1990 and 2016, regardless of TMJ arthritis status. Cumulative incidences of orofacial conditions were reported using Kaplan-Meier methods, and predictors for dentofacial deformity were identified using Cox proportional hazards analysis. RESULTS: Follow-up data from 351 subjects for 36 months were included in this study. Median age at first clinical examination was 6.6 years (interquartile range 4.8-9.9 years). Orofacial symptoms and dysfunctions were common findings at 36 months after the first clinical examination and 5 years after JIA onset, with a cumulative incidence of 38% and 53%, respectively. Dentofacial deformities were found in 35% of subjects at the 36-month follow-up and were significantly associated with the presence of orofacial dysfunction. CONCLUSION: Orofacial conditions were frequently observed in individuals with JIA and were represented in all JIA subcategories in this regional study. One-third of subjects had arthritis-induced dentofacial deformities that required orthopedic appliance treatment at the 36-month follow-up.
Authors: Xiaowen Niu; Julianne Moland; Thomas Klit Pedersen; Anders Ellern Bilgrau; Paolo M Cattaneo; Mia Glerup; Peter Stoustrup Journal: Pediatr Rheumatol Online J Date: 2022-04-27 Impact factor: 3.413
Authors: Lena Cetrelli; Athanasia Bletsa; Anette Lundestad; Elisabet Grut Gil; Johannes Fischer; Josefine Halbig; Paula Frid; Oskar Angenete; Ingrid Lillevoll; Annika Rosén; Karin B Tylleskär; Keio Luukko; Ellen Nordal; Anne Nordrehaug Åstrøm; Marit Slåttelid Skeie; Astrid Jullumstrø Feuerherm; Abhijit Sen; Marite Rygg Journal: BMC Oral Health Date: 2022-08-08 Impact factor: 3.747
Authors: J Fischer; M S Skeie; K Rosendahl; K Tylleskär; S Lie; X-Q Shi; E Grut Gil; L Cetrelli; J Halbig; L von Wangenheim Marti; M Rygg; P Frid; P Stoustrup; A Rosèn Journal: BMC Oral Health Date: 2020-10-13 Impact factor: 2.757