| Literature DB >> 30973558 |
Thomas M Haas1, Paul Ebensperger1, Verena B Eisenbeis1, Christoph Nopper1, Tobias Dürr1, Nikolaus Jork1, Nicole Steck1, Claudia Jessen-Trefzer2, Henning J Jessen1.
Abstract
A tunable chemoenzymatic strategy provides access to the entire class of magic spot nucleotides and modified analogues. The approach combines chemoselective bisphosphorylations using phosphoramidites with regioselective ribonuclease T2 cyclo-phosphate hydrolysis, leading to flexible and simple gram-scale operations.Entities:
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Year: 2019 PMID： 30973558 DOI： 10.1039/c9cc01688k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222