Literature DB >> 30968755

How Do Kidneys Adapt to a Deficit or Loss in Nephron Number?

Hadi Fattah1,2, Anita Layton3,4, Volker Vallon1,2.   

Abstract

A deficit or loss in the number of nephrons, the functional unit of the kidney, can induce compensatory growth and hyperfunction of remaining nephrons. An increase in single nephron glomerular filtration rate (SNGFR) aims to compensate but may be deleterious in the long term. The increase in SNGFR is determined by the dynamics of nephron loss, total remaining GFR, the body's excretory demand, and the functional capacity to sustain single nephron hyperfunction.

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Mesh：

Year:  2019        PMID： 30968755      PMCID： PMC6734068          DOI： 10.1152/physiol.00052.2018

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  52 in total

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Journal:  Br J Obstet Gynaecol       Date:  1992-04

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Journal:  Kidney Int       Date:  2000-08       Impact factor: 10.612

7.  Nature and severity of the glomerular response to nephron reduction is strain-dependent in mice.

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Journal:  Am J Pathol       Date:  1999-03       Impact factor: 4.307

Review 8.  High-protein diets: potential effects on the kidney in renal health and disease.

Authors:  Allon N Friedman
Journal:  Am J Kidney Dis       Date:  2004-12       Impact factor: 8.860

9.  Estimation of total glomerular number in stable renal transplants.

Authors:  Xavier Fulladosa; Francesc Moreso; Jose A Narváez; Josep M Grinyó; Daniel Serón
Journal:  J Am Soc Nephrol       Date:  2003-10       Impact factor: 10.121

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Authors:  Gunhild Keller; Gisela Zimmer; Gerhard Mall; Eberhard Ritz; Kerstin Amann
Journal:  N Engl J Med       Date:  2003-01-09       Impact factor: 91.245
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Review 1.  Sensing of tubular flow and renal electrolyte transport.

Authors:  Eric H J Verschuren; Charlotte Castenmiller; Dorien J M Peters; Francisco J Arjona; René J M Bindels; Joost G J Hoenderop
Journal:  Nat Rev Nephrol       Date:  2020-03-03       Impact factor: 28.314

2.  Three-Dimensional Kidney-on-a-Chip Assessment of Contrast-Induced Kidney Injury: Osmolality and Viscosity.

Authors:  Kipyo Kim; Beomgyun Jeong; Yun-Mi Lee; Hyung-Eun Son; Ji-Young Ryu; Seokwoo Park; Jong Cheol Jeong; Ho Jun Chin; Sejoong Kim
Journal:  Micromachines (Basel)       Date:  2022-04-28       Impact factor: 3.523

Review 3.  SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients.

Authors:  George Vasquez-Rios; Girish N Nadkarni
Journal:  Int J Nephrol Renovasc Dis       Date:  2020-10-28

4.  Impact of Size Matching Based on Donor-Recipient Height on Kidney Transplant Outcomes.

Authors:  Srijan Tandukar; Christine Wu; Sundaram Hariharan; Chethan Puttarajappa
Journal:  Transpl Int       Date:  2022-03-18       Impact factor: 3.842

Review 5.  Effects of SGLT2 Inhibitors on Kidney and Cardiovascular Function.

Authors:  Volker Vallon; Subodh Verma
Journal:  Annu Rev Physiol       Date:  2020-11-16       Impact factor: 19.318

Review 6.  Assessment of nephron number and single-nephron glomerular filtration rate in a clinical setting.

Authors:  Nobuo Tsuboi; Takaya Sasaki; Yusuke Okabayashi; Kotaro Haruhara; Go Kanzaki; Takashi Yokoo
Journal:  Hypertens Res       Date:  2021-02-01       Impact factor: 3.872

7.  Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models.

Authors:  Philipp Tauber; Frederick Sinha; Raffaela S Berger; Wolfram Gronwald; Katja Dettmer; Michaela Kuhn; Maximilian Trum; Lars S Maier; Stefan Wagner; Frank Schweda
Journal:  Front Pharmacol       Date:  2021-12-21       Impact factor: 5.810

Review 8.  Mitochondria in Diabetic Kidney Disease.

Authors:  Amna Ayesha Ahmad; Shayna Odeal Draves; Mariana Rosca
Journal:  Cells       Date:  2021-10-29       Impact factor: 6.600

Review 9.  Glomerular filtration rate as a kidney outcome of diabetic kidney disease: a focus on new antidiabetic drugs.

Authors:  Hyo Jin Kim; Sang Soo Kim; Sang Heon Song
Journal:  Korean J Intern Med       Date:  2022-04-04       Impact factor: 3.165

10.  Metals and Metallothionein Expression in Relation to Progression of Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka.

Authors:  S H Nandana P Gunawickrama; A Rajith N Silva; P G Chandra L Nanayakkara; K B Suneetha Gunawickrama; J M Kithsiri B Jayasekara; Naduviladath V Chandrasekharan
Journal:  Diseases       Date:  2022-06-12
  10 in total

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