Literature DB >> 3096805

Effect of teprenone on the content of phospholipids in gastric secretion in man.

M Aono, M Moriga, K Mizuta, H Uchino.   

Abstract

The phospholipid content of basal and pentagastrin-stimulated gastric secretion was measured in 9 healthy volunteers. One week oral administration of teprenone did not alter the gastric acid and pepsin secretion. The phospholipid content was increased by teprenone. Changes in subclasses of phospholipids in gastric mucus by teprenone treatment, namely, increased phosphatidylcholine and decreased lysophosphatidylcholine, were observed.

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Year:  1986        PMID： 3096805     DOI： 10.1007/bf02774627

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN： 0435-1339


  19 in total

1.  Gastric mucosal barrier: hydrophobic lining to the lumen of the stomach.

Authors:  B A Hills; B D Butler; L M Lichtenberger
Journal:  Am J Physiol       Date:  1983-05

2.  Enzymatic synthesis of mannosyl retinyl phosphate from retinyl phosphate and guanosine diphosphate mannose.

Authors:  G C Rosso; L De Luca; C D Warren; G Wolf
Journal:  J Lipid Res       Date:  1975-05       Impact factor: 5.922

3.  The transfer of mannose from guanosine diphosphate mannose to dolichol phosphate and protein by pig liver endoplasmic reticulum.

Authors:  J B Richards; F W Hemming
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

4.  Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats.

Authors:  M Murakami; K Oketani; H Fujisaki; T Wakabayashi; T Ohgo
Journal:  Arzneimittelforschung       Date:  1981

5.  Effects of the antiulcer drug geranylgeranylacetone on aspirin-induced gastric ulcers in rats.

Authors:  M Murakami; K Oketani; H Fujisaki; T Wakabayashi; T Ohgo; S Okabe
Journal:  Jpn J Pharmacol       Date:  1982-04

6.  Lipid composition of the gastric mucous barrier in the rat.

Authors:  A Slomiany; S Yano; B L Slomiany; G B Glass
Journal:  J Biol Chem       Date:  1978-06-10       Impact factor: 5.157

7.  Molecular species of phosphatidylcholine from rat gastric mucosa.

Authors:  M K Wassef; Y N Lin; M I Horowitz
Journal:  Biochim Biophys Acta       Date:  1979-04-27

8.  [Study on the protective effect of vitamin A on stress ulcer of the rat (author's transl)].

Authors:  V Schumpelick; E Farthmann
Journal:  Arzneimittelforschung       Date:  1976

Review 9.  Vitamin A and mucus secretion. A brief review of the effect of vitamin A on the biosynthesis of glycoproteins.

Authors:  L De Luca; G Wolf
Journal:  Int Z Vitaminforsch       Date:  1970

10.  THE ESTIMATION OF PEPSIN WITH HEMOGLOBIN.

Authors:  M L Anson; A E Mirsky
Journal:  J Gen Physiol       Date:  1932-09-20       Impact factor: 4.086
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  4 in total

1.  Effects of 16,16-dimethyl prostaglandin E2 on glycoprotein and lipid synthesis of gastric epithelial cells grown in a primary culture.

Authors:  E J Dial; Y C Kao; L M Lichtenberger
Journal:  In Vitro Cell Dev Biol       Date:  1991-01

2.  Geranylgeranylacetone induces cyclooxygenase-2 expression in cultured rat gastric epithelial cells through NF-kappaB.

Authors:  Tsutomu Nishida; Yuki Yabe; Hai Ying Fu; Yujiro Hayashi; Kayoko Asahi; Hiroshi Eguchi; Shingo Tsuji; Masahiko Tsujii; Norio Hayashi; Sunao Kawano
Journal:  Dig Dis Sci       Date:  2007-04-03       Impact factor: 3.487

3.  Geranylgeranylacetone attenuates cisplatin-induced reductions in cell viability by suppressing the elevation of intracellular p53 content without heat shock protein induction.

Authors:  Motofusa Hasegawa; Kazuhiro Ishiguro; Takafumi Ando; Hidemi Goto
Journal:  Nagoya J Med Sci       Date:  2012-02       Impact factor: 1.131

4.  Rebamipide, a cytoprotective drug, increases gastric mucus secretion in human: evaluations with endoscopic gastrin test.

Authors:  Katsunori Iijima; T Ichikawa; S Okada; M Ogawa; T Koike; S Ohara; T Shimosegawa
Journal:  Dig Dis Sci       Date:  2008-10-31       Impact factor: 3.199
  4 in total

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