Literature DB >> 30963803

Subretinal Transplant of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium on Nanostructured Fibrin-Agarose.

Ana B García Delgado1, Berta de la Cerda1, Julia Alba Amador2, Maria Lourdes Valdés Sánchez1, Beatriz Fernández-Muñoz2, Isabel Relimpio López3,4, Enrique Rodríguez de la Rúa3,4, Andrea Díez Lloret1, Sofia M Calado1, Rosario Sánchez Pernaute2, Shom S Bhattacharya1, Francisco J Díaz Corrales1.   

Abstract

IMPACT STATEMENT: In the promising field of cellular therapy for retinal degenerative diseases, a new biomaterial is proposed as a scaffold to grow and surgically introduce a monolayer of retinal pigment epithelial cells into the subretinal space, keeping the orientation of the cells for a proper functional integration of the transplant. The use of induced pluripotent stem cells as the starting material for retinal pigment epithelial cells is intended to advance toward a personalized medicine approach.

Entities:  

Keywords:  fibrin-agarose hydrogel; induced pluripotent stem cells; macular degeneration; retinal pigment epithelium; subretinal implant

Year:  2019        PMID: 30963803     DOI: 10.1089/ten.TEA.2019.0007

Source DB:  PubMed          Journal:  Tissue Eng Part A        ISSN: 1937-3341            Impact factor:   3.845


  6 in total

1.  Methodological Approach to Improve Surgical Outcomes of a Pig Subretinal Implantation Model.

Authors:  Fukutaro Mano; Jarel K Gandhi; Raphael Pereira da Silva; Aline Do Amaral Silva; Lucas Iezzi; Raymond Iezzi; Jose S Pulido; Alan D Marmorstein
Journal:  Transl Vis Sci Technol       Date:  2022-04-01       Impact factor: 3.048

Review 2.  Bioengineering strategies for restoring vision.

Authors:  Jasmina Cehajic-Kapetanovic; Mandeep S Singh; Eberhart Zrenner; Robert E MacLaren
Journal:  Nat Biomed Eng       Date:  2022-01-31       Impact factor: 25.671

3.  Fabrication and Evaluation of Gellan Gum/Hyaluronic Acid Hydrogel for Retinal Tissue Engineering Biomaterial and the Influence of Substrate Stress Relaxation on Retinal Pigment Epithelial Cells.

Authors:  Jina Youn; Joo Hee Choi; Sumi Lee; Wonchan Lee; Seong Won Lee; Wooyoup Kim; Youngeun Song; Nomin-Erdene Tumursukh; Jeong Eun Song; Gilson Khang
Journal:  Molecules       Date:  2022-08-27       Impact factor: 4.927

4.  Inactivation of human plasma alters the structure and biomechanical properties of engineered tissues.

Authors:  Cristina Rosell-Valle; María Martín-López; Fernando Campos; Jesús Chato-Astrain; Rafael Campos-Cuerva; Miguel Alaminos; Mónica Santos González
Journal:  Front Bioeng Biotechnol       Date:  2022-08-23

5.  A Systematic Review on Transplantation Studies of the Retinal Pigment Epithelium in Animal Models.

Authors:  Céline Koster; Kimberley E Wever; Philip E Wagstaff; Koen T van den Hirk; Carlijn R Hooijmans; Arthur A Bergen
Journal:  Int J Mol Sci       Date:  2020-04-14       Impact factor: 5.923

6.  Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish.

Authors:  Lorena Buono; Jorge Corbacho; Silvia Naranjo; María Almuedo-Castillo; Tania Moreno-Marmol; Berta de la Cerda; Estefanía Sanabria-Reinoso; Rocío Polvillo; Francisco-Javier Díaz-Corrales; Ozren Bogdanovic; Paola Bovolenta; Juan-Ramón Martínez-Morales
Journal:  Nat Commun       Date:  2021-06-23       Impact factor: 14.919

  6 in total

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