| Literature DB >> 30963803 |
Ana B García Delgado1, Berta de la Cerda1, Julia Alba Amador2, Maria Lourdes Valdés Sánchez1, Beatriz Fernández-Muñoz2, Isabel Relimpio López3,4, Enrique Rodríguez de la Rúa3,4, Andrea Díez Lloret1, Sofia M Calado1, Rosario Sánchez Pernaute2, Shom S Bhattacharya1, Francisco J Díaz Corrales1.
Abstract
IMPACT STATEMENT: In the promising field of cellular therapy for retinal degenerative diseases, a new biomaterial is proposed as a scaffold to grow and surgically introduce a monolayer of retinal pigment epithelial cells into the subretinal space, keeping the orientation of the cells for a proper functional integration of the transplant. The use of induced pluripotent stem cells as the starting material for retinal pigment epithelial cells is intended to advance toward a personalized medicine approach.Entities:
Keywords: fibrin-agarose hydrogel; induced pluripotent stem cells; macular degeneration; retinal pigment epithelium; subretinal implant
Year: 2019 PMID: 30963803 DOI: 10.1089/ten.TEA.2019.0007
Source DB: PubMed Journal: Tissue Eng Part A ISSN: 1937-3341 Impact factor: 3.845