| Literature DB >> 30962345 |
Anaïs Potron1,2,3, Didier Hocquet2,4,5, Pauline Triponney3, Patrick Plésiat6,2,3, Xavier Bertrand2,4, Benoit Valot2.
Abstract
Nineteen Proteus mirabilis isolates producing the carbapenemase OXA-23 were recovered over a 2-year period in 19 French hospitalized patients, of whom 12 had community onset infections. The isolates exhibited a slightly reduced susceptibility to carbapenems. Whole-genome analysis revealed that all 19 isolates formed a cluster compared to 149 other P. mirabilis isolates. Because of its susceptibility to carbapenems, this clone may be misidentified as a penicillinase producer while it constitutes a reservoir of the OXA-23-encoding gene in the community.Entities:
Keywords: OXA-23; Proteus mirabiliszzm321990; carbapenemase; clonality; spread
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Year: 2019 PMID: 30962345 PMCID: PMC6535531 DOI: 10.1128/AAC.00191-19
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191