Indigenous and non-Indigenous people experiencing homelessness and mental illness in two Canadian cities: A retrospective analysis and implications for culturally informed action.

OBJECTIVES: Indigenous people in Canada are not only over-represented among the homeless population but their pathways to homelessness may differ from those of non-Indigenous people. This study investigated the history and current status of Indigenous and non-Indigenous people experiencing homelessness and mental illness. We hypothesised that compared with non-Indigenous people, those who are Indigenous would demonstrate histories of displacement earlier in life, higher rates of trauma and self-medication with alcohol and other substances. DESIGN AND
SETTING: Retrospective data were collected from a sample recruited through referral from diverse social and health agencies in Winnipeg and Vancouver. PARTICIPANTS: Eligibility included being 19 years or older, current mental disorder and homelessness. MEASURES: Data were collected via interviews, using questionnaires, on sociodemographics (eg, age, ethnicity, education), mental illness, substance use, physical health, service use and quality of life. Univariate and multivariable models were used to model the association between Indigenous ethnicity and dependent variables.
RESULTS: A total of 1010 people met the inclusion criteria, of whom 439 self-identified as Indigenous. In adjusted models, Indigenous ethnicity was independently associated with being homeless at a younger age, having a lifetime duration of homelessness longer than 3 years, post-traumatic stress disorder, less severe mental disorder, alcohol dependence, more severe substance use in the past month and infectious disease. Indigenous participants were also nearly twice as likely as others (47% vs 25%) to have children younger than 18 years.
CONCLUSIONS: Among Canadians who are homeless and mentally ill, those who are Indigenous have distinct histories and current needs that are consistent with the legacy of colonisation. Responses to Indigenous homelessness must be developed within the context of reconciliation between Indigenous and non-Indigenous Canadians, addressing trauma, substance use and family separations. TRIAL REGISTRATION NUMBER: ISRCTN42520374, ISRCTN57595077, ISRCTN66721740. © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

A large sample and validated self-report measures.

First multisite investigation of distinct needs among Indigenous homeless.

Demonstration that Indigenous and non-Indigenous homeless individuals have needs that correspond to differences in their historical experiences.

Symptoms of mental illness and substance use and recollection of past events may have influenced responses.

Indigenous ethnicity may have been under-reported due to concerns regarding stigma or discrimination.

Background

Indigenous (The term ‘Indigenous’ will be used throughout this paper to collectively describe the Indigenous peoples of Canada, inclusive of those who identify as ‘Aboriginal’ or First Nations, Métis and Inuit. This term is used while also acknowledging the diversity of cultures, languages and traditions that exist among Indigenous Canadians) people are over-represented among homeless populations in every part of the world where these rates are documented.1 Indigenous people struggling with mental illness, substance use or homelessness often share experiences involving structural inequities and trauma related to colonisation. Despite a visible presence of Indigenous peoples in the urban homeless populations of North America, Australia and New Zealand, there is limited research investigating the prevalence and causes of Indigenous homelessness.1 Indigenous Australians comprise 9% of the homeless population compared with 3.3% of the general population. Similarly, in New Zealand, Maori homelessness has been reported to be five times that of non-Maori.1 In Canada, homelessness among Indigenous people is eight times more prevalent than among all others.2 Indigenous people comprise about 6% of British Columbia’s population, yet in 2018 accounted for 40% of Vancouver’s homeless of whom close to half are unsheltered (46%).3 The Vancouver area is home to approximately 62 000 Indigenous people representing 23% of B.C.’s Indigenous population.4 Women accounted for 53% of the Indigenous homeless people in Vancouver, and 46% were under 25.3 Homelessness among youth has increased in Vancouver, with those under 25 representing 24% of the overall homeless population.5

Pathways to homelessness integrate poverty, mental illness, addiction, lack of affordable housing and socioeconomic inequities.6–8 The high prevalence of mental illness among the homeless9 10 is related to sustained disinvestment in institutional models of care and insufficient attention to the design and implementation of community-based approaches to delivering housing and support.11 Fragmentation between systems responsible for healthcare and social services amplifies the challenges faced by people who are mentally ill and homeless.10 Many marginalised and homeless people must navigate a maze of multiple systems to receive essential supports, leading one scholar to describe them as ‘system survivors’.10 Multidisciplinary models integrating primary care and specialised services have been recommended for people with multiple and complex needs.12

Indigenous pathways to homelessness are likely inclusive of the above factors. In addition, current inequities in the health of Indigenous peoples are directly related to past and present colonial policies that created and sustain systemic racism, cultural oppression, disempowerment and dispossession of Indigenous peoples lands.2 6 13 The Indian Act (1876) and related policies served to dispossess Indigenous peoples of land, disrupt the practice and transmission of traditional knowledge, undermine the matriarchal role of women and remove generations of children from their communities into settings where abuse was widespread. Canada’s Truth and Reconciliation Commission (TRC) identified the residential school era as the beginning of intergenerational cycles of trauma for Indigenous Canadians,14 15 and concluded that the actions are taken under the Indian Act and related policies amounted to ‘cultural genocide’.14

Child welfare policies continue to separate Indigenous children from their families and communities. Indigenous youth are vastly over-represented in the child welfare system and foster care, disrupting Indigenous families and contributing to homelessness.2 In Canada, Indigenous children and youth are 15 times more likely to be in government care than non-Indigenous children and youth.15 The ‘60s scoop refers to a time at the height of the residential school era in the ‘50s and ‘60s, where an amendment to the Canadian Indian Act gave provinces authority over their child protection policies, leading to a dramatic increase in the number of Indigenous children in the child welfare system. Trauma arising from these experiences affects communities across generations.15

These differences have led to the development of a distinct definition of Indigenous homelessness in Canada: ‘Unlike the common colonialist definition of homelessness, Indigenous homelessness is not defined as lacking a structure of habitation; rather, it is more fully described and understood through a composite lens of Indigenous worldviews. These include: individuals, families and communities isolated from their relationships to land, water, place, family, kin, each other, animals, cultures, languages and identities. Importantly, Indigenous people experiencing these kinds of homelessness cannot culturally, spiritually, emotionally or physically reconnect with their indigeneity or lost relationships’.16 A related insight can be found in the final report of the TRC, which examined the urgent and complex relationships between Indigenous and non-Indigenous peoples in Canada and does not mention the term ‘homelessness’ at all, but includes the term ‘home’ 146 times, usually in the context of loss and enforced separation.14

Among relevant empirical studies, disparities have been reported concerning Indigenous peoples’ access to appropriate and responsive primary healthcare.17–19 Pervasive racism and discrimination against Indigenous peoples in the Canadian healthcare system has been widely reported and in many cases has led to Indigenous patients strategising for how to avoid racism before seeking care or avoiding care altogether.17 20 Despite the high need (HN) for mental health, substance use and healthcare among homeless populations there remain substantial gaps in research examining the implications of historical and current differences between Indigenous and non-Indigenous peoples as they relate to policies and services addressing homelessness. The need for further research into the effects of ethnicity on homelessness has been well established.21 Indeed, few studies have examined the potential upstream causal factors that contribute to the over-representation of Indigenous people among the homeless.1 Such information is essential to the development of effective policies.

The current study investigated differences between Indigenous and non-Indigenous people who experienced homelessness and mental illness, and whether differences are consistent with distinct trajectories leading to homelessness. We hypothesised that Indigenous participants would be more likely to have experienced homelessness earlier in life and have higher prevalence of trauma and substance use, and that non-Indigenous participants would be more likely to experience serious mental illness such as schizophrenia.

Methods

Data source and sample

The At Home/Chez Soi Study took place in five Canadian cities and enrolled participants who were homeless and mentally ill.22 23 The current study includes baseline data from Vancouver and Winnipeg, the sites with the highest proportions of Indigenous people who are homeless. Further details related to the trial protocols and methods that are not essential to the current study have been published elsewhere.22 23

Eligibility criteria included being a legal adult (19 years or older), current mental disorder and being absolutely or precariously housed. Absolute homelessness was defined as having no place to stay for more than seven nights and little likelihood of finding a place in the next month.22 Precarious housing referred to living in a rooming house, hotel or transitional housing and having at least two episodes of homelessness, as defined above, in the past year.22 23 Participants were recruited through referral from diverse agencies including: homeless shelters; drop-in centres; homeless outreach teams; hospitals; community mental health team and criminal justice programmes. Organisations that serve women, youth, Indigenous peoples and gay/lesbian/transgender were targeted to obtain a diverse sample.

An initial face-to-face interview was conducted to determine if referred individuals met the inclusion criteria. On meeting criteria, participants completed written informed consent obtained by the interviewer and were enrolled and administered the baseline questionnaire that included information on sociodemographics, mental illness, substance use, physical health, service use and quality of life. Participants were not eligible for recruitment if they could not give informed consent. Consent procedures were tested prior to study implementation24 and interviewers were trained by senior clinicians with ongoing support from a clinical psychologist and psychiatry resident. Interviews were postponed or rescheduled if a participant was unable to give informed consent to the study details (eg, randomisation) for any reason.23 Participants received a cash honorarium of US$30 on completion of the baseline interview and US$20 for each subsequent interview. Results are based on data from the baseline questionnaires of 497 Vancouver participants and 513 Winnipeg participants.

Patient and public involvement

Indigenous people and community stakeholders were engaged in the development and implementation of this research. Community meetings (including advertised open meetings) and six focus groups were conducted with key informants.23 In total, 58 individuals were convened and met with a facilitator who prepared reports of the proceedings. Focus group participants advised on procedures, reducing risks and maximising benefits to participants and on how to incorporate the expertise of individuals with direct experience of homelessness into the study. Narrative feedback from participants was incorporated into the grant application and the project. Service providers were also consulted extensively during the design of the research. More specifically, in Winnipeg, where Indigenous homelessness was a specific focus, an Indigenous research steering committee was created, composed of elders and traditional teachers, to provide cultural advice and guidance to the research team to ensure that Indigenous perspectives were incorporated. In addition, a Lived Experience Circle was created which honoured and promoted Indigenous lived experience through the research. In Winnipeg, persons with lived experience (PWLE) were involved in multiple roles on the project as representatives on an advisory committee and employed as research staff. PWLE assisted in facilitating integrated knowledge exchange, working with staff of the interventions and directly to bring patient perspectives into the research and interventions. Since completion of the trial, across all study sites findings have been reported at a variety of academic forums distributed to diverse audiences including provincial governments, municipalities, health authorities and community agencies. In April 2018, a forum was held where key members of community service organisations that work with Indigenous people who are homeless were invited to review study results, provide their recommendations and guide the interpretation of meaning. The current findings will be disseminated following publication via the established network of local service providers, stakeholders and participants of the research forum.

Variables of interest

Indigenous or Aboriginal ethnicity status was derived from self-report. Participants were asked if they identify as ‘Aboriginal’ and to check all that apply: Inuit, Métis, First Nations status, First Nations non-status, Indigenous from outside Canada and other. For the purposes of these analyses, participants who identified as any of these categories of ‘Aboriginal’ were considered to be Indigenous. The cluster of severe mental disorders includes at least one of current (ie, past month) psychotic disorder, mood disorder with psychotic features and hypomanic or manic episode, as identified through the MINI International Neuropsychiatric Interview 6.0 (MINI).25 The MINI is a structured, short diagnostic interview often used for psychiatric evaluation and outcome tracking, with an administrative time of about 15 min. The less severe cluster includes at least one of current major depressive episode, panic disorder and post-traumatic stress disorder (PTSD). In addition, diagnosis of alcohol and substance dependence was assessed determined using the MINI. Substance use severity in the past month was assessed using the Global Assessment of Individual Need-Substance Problem Scale, a 16-item subscale that integrates research and clinical assessment for people presenting for substance abuse treatment.22 Frequency of use included all illicit drugs and alcohol. Bloodborne infectious disease was based on a positive self-report diagnosis of HIV, hepatitis B or hepatitis C. Self-reported involvement with health services was collected for the past 6 months including visiting a: family doctor, psychiatrist, emergency room (ER) and being transported by ambulance to an ER. Access to healthcare was elicited by the questions ‘Is there a place that you usually go to when you’re sick or in need of advice about your health?’ and ‘In the past 6 months, was there ever a time when you needed healthcare but you did not receive it?’ Criminal justice services included: Contact with the police that did not result in arrest; contacts that resulted in arrest; or being held in a police cell for less than 24 hours. Rates of imprisonment were not differentiated from this item. However, further analysis of administrative records for the Vancouver sample found that 14% had been in custody during the 6 months prior to study recruitment.26 Participants were categorised as either moderate needs (MN) or HN). Inclusion in the HN category was based on a score of 62 or lower on the Multnomah Community Ability Scale (MCAS) or current bipolar or psychotic disorder as well as one of the following: legal involvement in the past year; substance dependence in the past month and two or more hospitalisations for mental illness in the past 5 years.27 All other eligible participants were categorised as MN in the study.22 The MCAS is a 17-item scale measuring the degree of functional ability through 17 indicators. Indicators are rated into a 5-point scale across health, coping, social and behavioural domains. Detailed descriptions and psychometric information for study instruments is published in the At Home/Chez Soi Trial protocol.22

Statistical analysis

Pearson χ2 or Fisher’s exact test were used to conduct comparisons between baseline sociodemographic characteristics for Vancouver and Winnipeg participants and to make comparisons between Indigenous and non-Indigenous participants. Comparisons of numeric variables (eg, age at enrolment) between groups were conducted using the Student’s t-test and Wilcoxon rank-sum test. Comparisons were conducted across sociodemographic variables, homelessness variables, mental health, substance use, health conditions and service use for individuals of Indigenous versus non-Indigenous ethnicity. Univariate and multivariate logistic regression analyses were used to model the independent associations between Indigenous ethnicity and a series of outcome variables. Statistical significance (variables that were significant at the p<0.05 level), as well as subjective assessment, was considered to select outcome variables for the multivariable logistic regression analyses. The multivariable model adjusted for potentially confounding variables which may have been unevenly distributed based on ethnicity.23 28 The following controlling variables were used for the multivariable model: age (continuous); gender (man, woman); need level (high, moderate); marital status (single, other); site (Vancouver, Winnipeg); education (completed high school, incomplete high school); have children (under age 18). Both unadjusted and adjusted odds ratios (UOR and AOR) and 95% CIs are reported. SPSS V.21 was used to conduct these analyses.

Results

Descriptive characteristics of participants recruited in Vancouver (n=497) and Winnipeg (n=513) are presented in table 1. In Vancouver, the mean age of participants was 41 years (SD=11) and the majority were male (73%), white (56%), single/never married (70%) and had not completed high school (57%). In Winnipeg, the mean age of participants (n=513) was 39 years (SD=11) and the majority were male (64%), Indigenous (71%), single/never married (70%) and had not completed high school (69%). Participants at the Vancouver and Winnipeg sites significantly differed with respect to: need level; gender; ethnicity; education; hospitalisations; arrests; housing status; mental illness severity and suicidality (p<0.05).

Table 1

Sociodemographic, mental health, substance use and service use characteristics for Vancouver and Winnipeg At Home Study participants (n=1010)

Variable	Vancouver Site N (%) 497 (49.2)	Winnipeg Site N (%) 513 (50.8)	P value
Need level
High need	297 (59.8)	199 (38.8)	<0.001
Moderate need	200 (40.2)	314 (61.2)
Gender
Male	359 (72.8)	326 (63.8)	0.002
Female	134 (27.2)	185 (36.2)
Age at enrolment
Youth	36 (7.2)	64 (12.5)	0.020
25–44 years	281 (56.5)	277 (54.0)
44 plus years	180 (36.2)	172 (33.5)
Ethnicity
Indigenous	77 (15.5)	362 (70.6)	<0.001
White	280 (56.3)	112 (21.8)
Mixed/other	140 (28.2)	39 (7.6)
Education
High school or higher	214 (43.3)	157 (30.7)	<0.001
Less than high school	280 (56.7)	354 (69.3)
Marital status
Single (never married)	343 (69.6)	359 (70.3)	0.971
Married/partner	25 (5.1)	25 (4.9)
Separated/widow/divorced	125 (25.4)	127 (24.9)
Have children (under 18)	122 (25.1)	238 (47.1)	<0.001
Hospitalised for mental illness over 6 months in past 5 years	57 (11.7)	23 (4.5)	<0.001
Hospitalised for mental illness over two times in the past 5 years	253 (52.7)	111 (21.9)	<0.001
Arrested/imprisoned/probation/community sanction in past 6 months	221 (45.2)	179 (35.0)	0.001
Spend one or more night in hospital, detox, shelter and jail in past 6 months	65 (84.4)	321 (88.7)	0.298
Length of homelessness lifetime
1–3 years	257 (52.3)	262 (53.0)	0.827
3 years plus	234 (47.7)	232 (47.0)
Length of homelessness longest single period
12 months	246 (50.1)	227 (46.9)	0.317
13–60 months	182 (37.1)	192 (39.7)
60 months plus	63 (12.8)	65 (13.4)
Age first homeless
18 years or less	110 (22.4)	138 (27.2)	0.173
19–30 years	158 (32.2)	151 (29.8)
31–40 years	94 (19.1)	106 (20.9)
Over 40 years	129 (26.3)	112 (22.1)
Housing status
Absolutely homeless	388 (78.1)	354 (69.1)	0.001
Precariously housed	109 (21.9)	158 (30.9)
Mental illness
Less severe mental illness	264 (53.1)	436 (85.0)	<0.001
Multiple mental disorders (≥2)	240 (48.3)	338 (65.9)	<0.001
Post-traumatic stress disorder	129 (26.0)	233 (45.4)	<0.001
Current suicidality (high)	373 (75.1)	447 (87.1)	<0.001
Chronic disease and service access
Bloodborne diseases	157 (31.9)	113 (22.2)	0.001
Two or more physical illness	402 (80.9)	458 (89.3)	<0.001
Have a regular medical doctor	320 (64.5)	337 (65.7)	0.695
Place you usually go when you are sick or need advice about your health	395 (80.8)	430 (84.1)	0.161
Needed healthcare, but did not receive it in past 6 months	209 (43.2)	278 (55.0)	<0.001
Substance use
Current alcohol dependence	29 (37.7)	261 (72.1)	<0.001
Current substance dependence	57 (74.0)	183 (50.6)	<0.001
Age first alcohol use (categorised by median) (>14; <13)	33 (44.0)	140 (39.9)	0.510
	42 (56.0)	211 (60.1)
Age first drug use (After >14; <13)	37 (49.3)	160 (47.1)	0.721
	38 (50.7)	180 (52.9)
Global Assessment of Individual Need score (0–3 less severe); (4–5 severe) substance use in past month	34 (48.6)	214 (62.8)	0.027
	36 (51.4)	127 (37.2)

Univariate comparisons between Indigenous (439) and non-Indigenous (571) samples from both study sites are presented in table 2. The majority of Indigenous participants met criteria for the MN condition (59%), were male (61%), had not completed high school (75%) and had a lifetime duration of homelessness greater than 3 years (52%). Compared with non-Indigenous participants, Indigenous participants were more likely to have children under the age of 18 (52% vs 25%) and were first homeless at a younger age (63% vs 51% reporting being first homeless before the age of 30).

Table 2

Sociodemographic, mental health, substance use and service use characteristics for Vancouver and Winnipeg At Home Study participants by Indigenous ethnicity (n=1010)

Variable	Indigenous N (%) 439 (43.5%)	Non-Indigenous N (%) 571 (56.5%)	P value
Need level
High need	180 (41.0)	316 (55.3)	<0.001
Moderate need	259 (59.0)	255 (44.7)
Gender
Male	265 (61.1)	420 (73.7)	<0.001
Female	169 (38.9)	150 (26.3)
Age at enrolment
Youth	53 (12.1)	47 (8.2)	0.043
25–44 Years	266 (60.6)	292 (51.1)
44 plus years	120 (27.3)	232 (40.6)
Education
High school or higher	110 (25.2)	261 (46.0)	<0.001
Less than high school	327 (74.8)	307 (54.0)
Marital status
Single (never married)	313 (71.6)	389 (68.6)	0.018
Married/partner	29 (6.6)	21 (3.7)
Separated/widow/divorced	95 (21.7)	157 (27.7)
Have children (under 18)	222 (51.5)	138 (24.6)	<0.001
Hospitalised for mental illness over 6 months in past 5 years	22 (5.1)	58 (10.3)	0.003
Hospitalised for mental illness over two times in the past 5 years	107 (24.7)	257 (46.5)	<0.001
Arrested/imprisoned/probation/community sanction in past 6 months	171 (39.0)	229 (40.7)	0.585
Spent one or more nights in hospital, detox, shelter and jail in past 6 months	386 (87.9)	510 (89.6)	0.393
Length of homelessness lifetime
1–3 years	205 (48.3)	314 (56.0)	0.018
3 years plus	219 (51.7)	247 (44.0)
Length of homelessness longest single period
12 months	189 (45.2)	284 (51.0)	0.074
13–60 months	166 (39.7)	208 (37.3)
60 months plus	63 (15.1)	65 (11.7)
Age first homeless
18 years or less	130 (30.0)	118 (20.9)	<0.001
19–30 years	142 (32.7)	167 (29.6)
31–40 years	86 (19.8)	114 (20.2)
Over 40 years	76 (17.5)	165 (29.3)
Housing status
Absolutely homeless	309 (70.4)	433 (76.0)	0.046
Precariously housed	130 (29.6)	137 (24.0)
Mental illness
Less severe mental illness	370 (84.3)	330 (57.8)	<0.001
Multiple mental disorders (≥2)	290 (66.1)	288 (50.4)	<0.001
Post-traumatic stress disorder	215 (49.0)	147 (25.8)	<0.001
Current suicidality (high)	381 (86.8)	439 (76.9)	<0.001
Chronic disease and service access
Bloodborne diseases	122 (28.1)	148 (26.1)	0.488
Two or more physical illness	389 (88.6)	471 (82.5)	0.007
Have a regular medical doctor	299 (68.1)	358 (62.8)	0.080
Place you usually go when you are sick or need advice about your health	373 (85.4)	452 (80.3)	0.036
Needed healthcare, but did not receive it in past 6 months	224 (51.7)	263 (47.3)	0.167
Substance use
Current alcohol dependence	290 (66.1)	153 (26.8)	<0.001
Current substance dependence	240 (54.7)	289 (50.6)	0.201
Age first alcohol use (categorised by median) (>14; <13)	173 (40.6)	301 (55.4)	<0.001
	253 (59.4)	242 (44.6)
Age first drug use (After >14; <13)	197 (47.5)	327 (63.1)	<0.001
	218 (52.5)	191 (36.9)
Global Assessment of Individual Need score (0–3 less severe); (4–5 severe) substance use in past month	248 (60.3)	405 (75.4)	<0.001
	163 (39.7)	132 (24.6)

Effect size estimates as (UOR and AOR) and 95% CIs are presented in table 3. Results from multivariable logistic regression analyses indicate that self-reported Indigenous ethnicity independently predicted a younger age first homeless <25 years (AOR 1.56; 95% CI 1.06 to 2.27), a longer lifetime duration of homelessness (more than 3 years) (AOR 1.41; 95% CI 1.01 to 2.0), PTSD (AOR 1.91; 95% CI 1.35 to 2.70), not meeting criteria for ‘severe’ mental disorder (AOR 1.72; 95% CI 1.16 to 2.56), alcohol dependence (AOR 2.64, 95% CI 1.90 to 3.68), more severe substance use in the past month (AOR 2.43; 95% CI 1.67 to 3.56) and infectious bloodborne diseases (AOR 1.59; 95% CI 1.08 to 2.34).

Table 3

Logistic regression analysis to estimate the association between Indigenous ethnicity and homelessness, mental and physical illness and service utilisation among Vancouver and Winnipeg ‘At Home’ participants (n=1010)

Dependent variable	Unadjusted OR (95% CI)	P value	Adjusted† OR (95% CI)	P value
Homelessness
Age first homeless (<25 years)	1.54 (1.19 to 1.98)	0.001*	1.56 (1.06 to 2.27)	0.023*
Lifetime duration of homelessness (More than 3 years)	1.36 (1.05 to 1.75)	0.018*	1.41 (1.01 to 2.0)	0.041*
Longest single episode of homelessness (more than 1 year)	1.26 (0.98 to 1.63)	0.074	1.10 (0.79 to 1.52)	0.590
Mental illness
Post-traumatic stress disorder	2.76 (2.12 to 3.60)	<0.001*	1.91 (1.35 to 2.70)	<0.001*
Multiple mental disorders (>2)	1.91 (1.48 to 2.47)	<0.001*	1.27 (0.90 to 1.78)	0.169
Less severe mental disorder	3.92 (2.89 to 5.32)	<0.001*	1.72 (1.16 to 2.56)	0.008*
Severe mental disorder	0.46 (0.35 to 0.59)	<0.001*	0.73 (0.50 to 1.07)	0.104
Substance use
Current alcohol dependence	5.32 (4.06 to 6.97)	<0.001*	2.64 (1.90 to 3.68)	<0.001*
Current substance dependence	1.18 (0.92 to 1.51)	0.201	1.31 (0.92 to 1.86)	0.132
Age first alcohol use (after >14; <13)	1.82 (1.41 to 2.35)	<0.001*	1.35 (0.97 to 1.87)	0.077
Age first drug use (After >14; <13)	1.90 (1.46 to 2.46)	<0.001*	1.68 (1.20 to 2.37)	0.003*
Global Assessment of Individual Need score (0–3 less severe); (4–5 severe) substance use in past month	2.02 (1.53 to 2.67)	<0.001*	2.43 (1.67 to 3.56)	<0.001*
Chronic disease
Infectious (bloodborne) disease—HIV, hepatitis C or hepatitis B	1.10 (0.83 to 1.46)	0.489	1.59 (1.08 to 2.34)	0.018*
Multiple comorbid conditions (two or more)	1.65 (1.15 to 2.40)	0.007*	1.02 (0.64 to 1.64)	0.923
Three or more physical conditions	1.90 (1.41 to 2.60)	<0.001*	1.28 (0.87 to 1.90)	0.212
Service use
Have regular medical doctor	1.27 (0.97 to 1.65)	0.080	1.49 (1.05 to 2.10)	0.024*
Needed healthcare but did not receive it in past 6 months	1.19 (0.93 to 1.54)	0.167	0.79 (0.57 to 1.10)	0.166
Taken to emergency room (ER) in P6M	1.21 (0.94 to 1.56)	0.145	1.37 (0.99 to 1.92)	0.062
Multiple ER visit (>1 visit)	0.89 (0.68 to 1.16)	0.382	1.07 (0.75 to 1.51)	0.719
Taken by ambulance to hospital P6M	1.29 (1.0 to 1.67)	0.052	1.86 (1.32 to 2.61)	<0.001*
Arrested in the past 6 months	0.89 (0.68 to 1.17)	0.416	1.10 (0.76 to 1.60)	0.604
Court appearances P6M	0.95 (0.73 to 1.25)	0.717	1.06 (0.74 to 1.52)	0.761
Participated in justice service programmes (eg, drug treatment court, mental health court, Indigenous justice)	1.30 (0.86 to 1.96)	0.218	1.13 (0.66 to 1.94)	0.652

*P<0.05.

†Controlled for age (continuous), gender (male, female), need level (high, moderate), marital status (single, other), site (Vancouver, Winnipeg), education (high school or higher, less than high school), have children (under 18).

Discussion

Our findings suggest that the trajectories leading to homelessness among Indigenous and non-Indigenous people differ meaningfully from each other, and that they can be understood as consequences of harmful government policies. Consistent with the legacy of colonisation and cultural genocide, when compared with others, Indigenous participants experienced homelessness and first used substances at a younger age, spent more of their lives living homeless, were more frequently taken by ambulance to hospital and were more likely to meet criteria for PTSD, severe substance use and have an infectious disease. Conversely, non-Indigenous participants were more likely to meet criteria for schizophrenia or other severe mental illness, suggesting links to deinstitutionalisation and the inadequate implementation of alternative community-based treatment. These differences require consideration in the development of culturally appropriate housing and support services that are specific to the needs of Indigenous and non-Indigenous peoples. Programmes for Indigenous people must prevent homelessness early in life, stemming the grossly disproportionate rates of removal of Indigenous children and youth into state-administered foster care.15 29

Within our sample of Indigenous people, we found that almost half of the participants met criteria for PTSD (49% compared with 26% among non-Indigenous), consistent with a significant body of literature documenting the historical and continuing trauma experienced by Indigenous people in Canada.5 30 31 Bombay et al 31 proposed that trauma can be transmitted across generations, based on findings that children of trauma survivors were more likely to have negative responses to stressors and more likely to develop PTSD or depression as a result.30 31 Intergenerational trauma represents a complex subtype of PTSD that must be addressed in housing interventions for Indigenous people.

Indigenous homeless participants in our study were significantly more likely to have used drugs at a younger age (13 years) compared with non-Indigenous participants. Indigenous participants were also more likely to report severe substance use in the past month. These findings are consistent with research involving non-homeless samples and showing that Indigenous youth compared with non-Indigenous youth have a higher likelihood of experimenting with substances at a younger age and using substances persistently into adulthood.32 33 Early initiation into drug use poses a significant risk for adverse outcomes such as infectious disease and other morbidity or mortality. Youth who initiated injection drug use at an earlier age have been found to be more likely to become infected with HIV and hepatitis C, demonstrating the need for targeted and early intervention for youth at risk of drug use.34 Observers have consistently reported that Indigenous youth are at disproportionately high risk for problematic substance use. However, few studies have investigated the protective factors related to substance use trajectories for Indigenous youth.35 Mainstream substance use treatment models have demonstrated limited success for Indigenous people.36 This may be because the factors responsible for substance use, (as well as homelessness and trauma) are unique to the experience of Indigenous people, and require ‘treatments’ that restore and rebuild Indigenous culture and rights. Approaches that create reconnection to community, culture and traditions have been shown to have a positive impact on substance use.36 Rawana and Ames35 reported that optimism, participation in recreational activities and attendance at religious or spiritual services were found to be protective against alcohol misuse for Indigenous youth. Prevention and early intervention of problematic substance use among Indigenous youth is urgently required in on-reserve and urban settings. Culturally, relevant curricula increased access to psychosocial supports, youth recreation and peer support models and trauma-informed services are also required.

In 2016 in the Metro Vancouver homeless count, homeless youth had increased to the highest level recorded in the region with 397, or 24% of the overall homeless population, under the age of 25. Youth reported that they had been affected by the lack of youth services or cuts to youth programmes from one or more levels of government.37 Street-involved youth often fall between services tailored to children or adults, and this issue is further complicated for Indigenous youth in the child welfare system who age out of many system supports on adulthood.28 38 Developmental resources grounded in Indigenous cultural practices are required to prevent homelessness among youth who are transitioning from foster care settings and also to support youth who experienced trauma in foster care settings.28 38

Indigenous participants in both sites were significantly more likely than non-Indigenous people to have a regular medical doctor and were also more likely to have been taken to the hospital by an ambulance in the past 6 months. This seemingly contradictory finding may indicate that medical care alone is insufficient to prevent acute emergencies caused by environmental, social and historical harms. Moreover, ER visits may be for reasons other than those typically addressed in a primary care setting such as acute psychotic symptoms, overdose, acute trauma and other serious health complications caused by long-term homelessness. Further research is required to investigate the impact of stigma and discrimination on service utilisation for Indigenous people who are homeless and the need for culturally safe services for this population.

The use of ambulance services for those who are homeless and mentally ill is indicative of the lack of essential supports to sustain wellness. Consistent with research with non-homeless samples, we found that Indigenous participants were more likely than non-Indigenous people to report positive status for HIV, hepatitis C or hepatitis B Virus.39 40 Marshall et al examined HIV prevalence among street-involved youth and found that Indigenous ethnicity was a correlate of HIV infection and that hepatitis C coinfection was less common among Indigenous participants.39 Indigenous people also face disparities in HIV outcomes and treatment, as they are likely to be diagnosed and initiate treatment later than non-Indigenous patients. Indigenous people have been noted to suffer higher mortality even after receiving antiretroviral treatment, suggesting that social determinants may need to be addressed in order to realise the expected effectiveness of medical treatment.40 Interventions must consider the intergenerational context of Indigenous homelessness, and promote the health of children through investments in families and communities.

This analysis has strengths and limitations. Strengths of the study include a large sample size, structured diagnostic interviews and self-report measures validated against administrative data sources.26 Limitations include the possibility that current mental illness or substance use symptoms may have compromised some participant responses. Although participants were asked if they were First Nations, Inuit, Métis and status versus non-status, the current study did not allow for analysis to elicit unique differences between these smaller and distinct groups. It is recommended that further research investigate the differences between First Nations, Métis and Inuit service needs as well as differences between those recognised as status and non-status under the Indian Act to elucidate the diversity of service needs within Indigenous groups. Finally, we relied on self-reported ethnicity and it is possible that Indigenous people may not have self-identified due to concerns related to stigma and discrimination.

Implications

Pathways leading to homelessness differ meaningfully between Indigenous and non-Indigenous adults who meet criteria for current homelessness and mental illness. Consistent with our hypotheses, Indigenous participants experienced homelessness at a younger age, were homeless longer, had greater substance-related problems, less formal education, more health emergencies and higher rates of infectious disease than non-Indigenous participants. Indigenous participants were also significantly more likely to satisfy our study’s ‘mental illness’ criterion with PTSD, while non-Indigenous participants were more likely to meet criteria for schizophrenia or bipolar disorder. Our findings are consistent with the view that solutions to Indigenous homelessness—both prevention and treatment—must involve practices that restore social and cultural power to Indigenous communities. By contrast, non-Indigenous participants showed strong indications for the appropriateness of housing and assertive community treatment, as promised by governments during the era of deinstitutionalisation. Further research is needed to replicate these findings in other regions and where the historical experiences of Indigenous peoples differ based on varying degrees of political and social autonomy and the preservation of cultural practices.