Literature DB >> 30961428

Multimodal Analgesia Protocol after Head and Neck Surgery: Effect on Opioid Use and Pain Control.

Eugenie Du1, Zainab Farzal1, Elizabeth Stephenson2, April Tanner1, Katherine Adams2, Douglas Farquhar1, Mark Weissler1, Samip Patel1, Jeffrey Blumberg1, Maryam Jowza3, Trevor Hackman1, Adam Zanation1.   

Abstract

OBJECTIVE: To assess the effect that implementation of a multimodal analgesic plan has on opioid requirements and pain control in head and neck (H&N) surgery patients. STUDY
DESIGN: Prospective cohort.
SETTING: Tertiary academic hospital. SUBJECTS AND METHODS: An institutional review board (IRB)-approved quality improvement initiative was undertaken to implement a multimodal analgesic protocol for all admitted H&N surgery patients starting November 2017. Postprotocol data from January to May 2018 were compared to preprotocol data from May to October 2017. Data were obtained from the electronic health records as well as through preoperative and postoperative surveys. Average pain scores and opioid use in morphine milligram equivalents (MMEs) before and after protocol implementation were compared.
RESULTS: In total, 139 postprotocol patients were compared to 89 preprotocol patients. The adjusted MMEs in the first 24 hours after surgery decreased significantly from 93.7 mg to 58.6 mg (P = .026) with protocol implementation. When averaged over the length of stay (MME/hospital day), the change was no longer statistically significant (57.9 vs 46.8 mg, P = .211). The average pain score immediately after surgery and on day of discharge did not change with protocol implementation.
CONCLUSION: Implementation of a multimodal analgesia plan reduced opioid use immediately after surgery but not over the course of hospitalization without any change in reported pain scores. This study shows that multimodal opioid-sparing analgesia after H&N surgery is feasible. Future studies are needed further refine the optimal analgesic strategy for H&N patients and assess the long-term efficacy, safety, and cost of such regimens.

Entities:  

Keywords:  head and neck surgery; multimodal analgesia protocol; opioid; pain control

Year:  2019        PMID: 30961428     DOI: 10.1177/0194599819841885

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  3 in total

1.  Association Between Multimodal Analgesia Administration and Perioperative Opioid Requirements in Patients Undergoing Head and Neck Surgery With Free Flap Reconstruction.

Authors:  Catherine N Vu; Carol M Lewis; Neil S Bailard; Ravish Kapoor; M Laura Rubin; Gang Zheng
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2020-06-18       Impact factor: 6.223

Review 2.  Guide to Enhanced Recovery for Cancer Patients Undergoing Surgery: Head and Neck Cancer.

Authors:  Anirudh Saraswathula; Christine G Gourin; Peter S Vosler
Journal:  Ann Surg Oncol       Date:  2021-04-23       Impact factor: 4.339

Review 3.  Nonopioid perioperative analgesia in head and neck cancer surgery: A systematic review.

Authors:  Beatrice C Go; Cammille C Go; Kevin Chorath; Alvaro Moreira; Karthik Rajasekaran
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2022-05-09
  3 in total

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