Koji Takahashi1, Osamu Tanaka1, Yosuke Kudo2, Eriko Sugawara2, Ken Johkura1,2. 1. a Department of Clinical Laboratory , Yokohama Brain and Spine Center , Yokohama , Japan. 2. b Department of Neurology , Yokohama Brain and Spine Center , Yokohama , Japan.
Abstract
BACKGROUND: Characteristics of vestibular evoked myogenic potentials (VEMPs) depend on stimulus conditions. OBJECTIVE: To determine the optimal stimulus conditions for cervical and ocular VEMPs. METHODS: Participants were 23 healthy subjects. We compared air-conducted cervical and ocular VEMPs elicited by various tone-burst conditions (frequencies 500-1,000 Hz, rise/fall times 1-2 ms, and plateau times 0-6 ms) with an intensity of 105 dB normal hearing level. Effects of simultaneous contralateral masking noise on VEMPs were also evaluated. RESULTS: The largest cervical VEMP amplitudes were elicited by 500-750 Hz and 2-6 ms plateau time-tone-bursts, and the largest ocular VEMP amplitudes by 750 Hz and 2-4 ms plateau time-tone-bursts. Repeatability of the latency was better at 1 ms than at 2 ms rise/fall time in both VEMPs. In both VEMPs, masking noise reduced amplitude, and in ocular VEMP, amplitudes were significantly larger at the left ear stimulation than the right. CONCLUSION: Optimal tone-burst stimulation for both VEMPs seemed to be 500-750 Hz frequency and 1/2/1 ms rise/plateau/fall time without contralateral masking noise. Ocular VEMP amplitudes from left ear stimulation were originally larger than those from right ear stimulation.
BACKGROUND: Characteristics of vestibular evoked myogenic potentials (VEMPs) depend on stimulus conditions. OBJECTIVE: To determine the optimal stimulus conditions for cervical and ocular VEMPs. METHODS:Participants were 23 healthy subjects. We compared air-conducted cervical and ocular VEMPs elicited by various tone-burst conditions (frequencies 500-1,000 Hz, rise/fall times 1-2 ms, and plateau times 0-6 ms) with an intensity of 105 dB normal hearing level. Effects of simultaneous contralateral masking noise on VEMPs were also evaluated. RESULTS: The largest cervical VEMP amplitudes were elicited by 500-750 Hz and 2-6 ms plateau time-tone-bursts, and the largest ocular VEMP amplitudes by 750 Hz and 2-4 ms plateau time-tone-bursts. Repeatability of the latency was better at 1 ms than at 2 ms rise/fall time in both VEMPs. In both VEMPs, masking noise reduced amplitude, and in ocular VEMP, amplitudes were significantly larger at the left ear stimulation than the right. CONCLUSION: Optimal tone-burst stimulation for both VEMPs seemed to be 500-750 Hz frequency and 1/2/1 ms rise/plateau/fall time without contralateral masking noise. Ocular VEMP amplitudes from left ear stimulation were originally larger than those from right ear stimulation.
Entities:
Keywords:
Cervical vestibular evoked myogenic potential; air conducted sound; ocular vestibular evoked myogenic potential; tone burst; white noise
Authors: Magdalena Sosna-Duranowska; Grazyna Tacikowska; Elzbieta Gos; Anna Krupa; Piotr Henryk Skarzynski; Henryk Skarzynski Journal: Front Neurol Date: 2021-05-21 Impact factor: 4.003