| Literature DB >> 30956588 |
Muhammad Ajmal Panezai1, Charles Owen1, Harold M Szerlip1.
Abstract
Ifosfamide-induced proximal tubular nephropathy can present as a spectrum of disease, from isolated hyperaminoaciduria to a partial or complete Fanconi syndrome. We report a case of ifosfamide-induced partial Fanconi syndrome in a man with metastatic progressive Ewing sarcoma and put forth a hypothesis on the mechanism.Entities:
Keywords: Acrolein; Ewing sarcoma; Fanconi syndrome; Na-K-ATPase; chloroacetaldehyde; hyperaminoaciduria; ifosfamide; nephrotoxicity; proximal tubulopathy
Year: 2019 PMID： 30956588 PMCID： PMC6442879 DOI： 10.1080/08998280.2018.1536020
Source DB: PubMed Journal: Proc (Bayl Univ Med Cent) ISSN： 0899-8280