Liang Zhang1, Song Zhang2, Izumi Maezawa3, Sergey Trushin1, Paras Minhas1, Matthew Pinto1, Lee-Way Jin3, Keshar Prasain4, Thi D T Nguyen4, Yu Yamazaki5, Takahisa Kanekiyo5, Guojun Bu5, Benjamin Gateno1, Kyeong-Ok Chang6, Karl A Nath7, Emirhan Nemutlu8, Petras Dzeja2, Yuan-Ping Pang9, Duy H Hua4, Eugenia Trushina10. 1. Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA. 2. Division of Cardiovascular Research, Mayo Clinic, Rochester, MN 55905, USA. 3. MIND Institute, University of California Davis, Sacramento, CA 95814, USA; Department of Pathology, University of California Davis, Sacramento, CA 95814, USA. 4. Department of Chemistry, CBC Building, Kansas State University, Manhattan, KS 66506, USA. 5. Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. 6. Department of Diagnostic Medicine Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. 7. Department of Nephrology, Mayo Clinic, Rochester, MN 55905, USA. 8. Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Sihhiye, Ankara 06100, Turkey. 9. Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. 10. Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: Trushina.Eugenia@mayo.edu.
In the version of this article originally published, in Supplementary Tables 1 and 2 CP2 concentrations were incorrectly presented in μM instead of nM. Tables are included here to reflect correct values including additional data for independent concentration evaluation. The mistake was introduced due to an error in the concentration of the standard used for the HPLC quantification. Additionally, in the Results section, the sentence “Average concentration of CP2 in the brain of new-born mice was ~90 μM, and in adult mice ~130 μM …” should be replaced with: “Average concentration of CP2 in the brain of new-born mice was ~90 nM, and in adult mice ~130 nM …”. Since CP2 was used as a model compound for a proof of concept studies, this mistake will not impact any preclinical developments.
Authors: Andrea Stojakovic; Sergey Trushin; Anthony Sheu; Layla Khalili; Su-Youne Chang; Xing Li; Trace Christensen; Jeffrey L Salisbury; Rachel E Geroux; Benjamin Gateno; Padraig J Flannery; Mrunal Dehankar; Cory C Funk; Jordan Wilkins; Anna Stepanova; Tara O'Hagan; Alexander Galkin; Jarred Nesbitt; Xiujuan Zhu; Utkarsh Tripathi; Slobodan Macura; Tamar Tchkonia; Tamar Pirtskhalava; James L Kirkland; Rachel A Kudgus; Renee A Schoon; Joel M Reid; Yu Yamazaki; Takahisa Kanekiyo; Song Zhang; Emirhan Nemutlu; Petras Dzeja; Adam Jaspersen; Ye In Christopher Kwon; Michael K Lee; Eugenia Trushina Journal: Commun Biol Date: 2021-01-08
Authors: Steven N Austad; Scott Ballinger; Thomas W Buford; Christy S Carter; Daniel L Smith; Victor Darley-Usmar; Jianhua Zhang Journal: Acta Pharm Sin B Date: 2021-06-30 Impact factor: 11.413