| Literature DB >> 30955598 |
Katarzyna Rafińska1, Paweł Pomastowski2, Joanna Rudnicka3, Aneta Krakowska4, Audrius Maruśka5, Monika Narkute6, Bogusław Buszewski7.
Abstract
The aim of this study was to evaluate chemical and biological potential of garden cress (Lepidium sativum L.) to receive valuable plant extracts with potential application in pharmacy or food industry. Four techniques of extraction and three environmentally friendly solvents such as water, supercritical CO2 and ethanol have been tested. Biological activity and chemical profile were evaluated in obtained extracts. GC/MS analysis showed that SFE extract from dried sprouts of L. sativum was especially rich in such glucosinolate derivatives as benzyl cyanide and benzyl thiocyanate. However, the extract obtained from freeze-dried sprouts by SFE with addition of 96% ethanol as co-solvent was especially rich in flavonoids and simultaneously exhibited the best antimicrobial activity. Comparison of MALDI-TOF-MS spectra of all obtained extracts clearly indicates that both SFE and maceration with water are the most selective techniques of extraction due to the lowest level of interfering substances with high molecular masses.Entities:
Keywords: Biological activity; Extraction methods; GC/MS analysis; Lepidium sativum L.; MALDI-TOF-MS analysis
Mesh：
Substances：
Year: 2019 PMID： 30955598 DOI： 10.1016/j.foodchem.2019.03.025
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514