| Literature DB >> 3095331 |
S Angsubhakorn, P Sathiropas, N Bhamarapravati.
Abstract
The interaction between aflatoxin and malaria was tested for its usefulness as a model for hepatic tumor induction in rats. Male Buffalo rats which received aflatoxin B1 (AFB1) followed by Plasmodium berghei infection developed more preneoplastic lesions in the liver compared to those given AFB1 alone. No preneoplastic lesions were found in the liver of control and malarial-treated animals. These findings suggest that the malarial parasite facilitates liver tumor development initiated by AFB1 in rats.Entities:
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Year: 1986 PMID： 3095331 DOI： 10.1007/bf00404403
Source DB: PubMed Journal: J Cancer Res Clin Oncol ISSN： 0171-5216 Impact factor: 4.553