Literature DB >> 3095282

Recombinant human granulocyte colony-stimulating factor induces granulocytosis in vivo.

M Fujisawa, Y Kobayashi, T Okabe, F Takaku, Y Komatsu, S Itoh.   

Abstract

Recombinant human granulocyte colony-stimulating factor (G-CSF) was prepared and its granulopoietic effects on mice were examined. When mice were injected intraperitoneally with the G-CSF daily for 14 days, marked granulocytosis occurred in the mice. The number of progenitor cells (CFU-C) was remarkably increased in the spleen. The results suggest that G-CSF plays a central role in granulocyte production in vivo.

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Year:  1986        PMID： 3095282

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  12 in total

Review 1.  G-CSF: status quo and new indications.

Authors:  F Herrmann
Journal:  Infection       Date:  1992 Jul-Aug       Impact factor: 3.553

Review 2.  Preclinical and clinical studies with the hematopoietic colony-stimulating factors and related interleukins.

Authors:  H E Broxmeyer; S Vadhan-Raj
Journal:  Immunol Res       Date:  1989       Impact factor: 2.829

3.  Therapeutic efficacy of granulocyte colony-stimulating factor alone and in combination with antibiotics against Pseudomonas aeruginosa infections in mice.

Authors:  H Yasuda; Y Ajiki; T Shimozato; M Kasahara; H Kawada; M Iwata; K Shimizu
Journal:  Infect Immun       Date:  1990-08       Impact factor: 3.441

Review 4.  Recombinant granulocyte colony-stimulating factor (rG-CSF). A review of its pharmacological properties and prospective role in neutropenic conditions.

Authors:  L M Hollingshead; K L Goa
Journal:  Drugs       Date:  1991-08       Impact factor: 9.546

5.  Granulocyte colony-stimulating factor does not enhance phagocytosis or microbicidal activity of human mature polymorphonuclear neutrophils in vitro.

Authors:  N Shimono; K Okada; D Takeda; K Eguchi; H Misumi; Y Sawae; Y Niho
Journal:  Clin Diagn Lab Immunol       Date:  1994-09

6.  In vivo activation of neutrophil function in hamsters by recombinant human granulocyte colony-stimulating factor.

Authors:  A M Cohen; D K Hines; E S Korach; B J Ratzkin
Journal:  Infect Immun       Date:  1988-11       Impact factor: 3.441

7.  Identification and characterization of receptors for granulocyte colony-stimulating factor on human placenta and trophoblastic cells.

Authors:  H Uzumaki; T Okabe; N Sasaki; K Hagiwara; F Takaku; M Tobita; K Yasukawa; S Ito; Y Umezawa
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

Review 8.  The dark side of granulocyte-colony stimulating factor: a supportive therapy with potential to promote tumour progression.

Authors:  Belinda Yeo; Andrew D Redfern; Kellie A Mouchemore; John A Hamilton; Robin L Anderson
Journal:  Clin Exp Metastasis       Date:  2018-07-02       Impact factor: 5.150

9.  Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines.

Authors:  R Alitalo; L C Andersson; C Betsholtz; K Nilsson; B Westermark; C H Heldin; K Alitalo
Journal:  EMBO J       Date:  1987-05       Impact factor: 11.598

10.  Enhanced antitumor effect of recombinant human tumor necrosis factor in combination with recombinant human granulocyte colony-stimulating factor in BALB/c mice.

Authors:  M Maeda; N Watanabe; N Tsuji; Y Tsuji; T Okamoto; H Sasaki; S Akiyama; Y Niitsu
Journal:  Jpn J Cancer Res       Date:  1993-08
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