Literature DB >> 3095279

Detection of amplified DNA sequences in gastric cancers by a DNA renaturation method in gel.

H Nakatani, E Tahara, T Yoshida, H Sakamoto, T Suzuki, H Watanabe, M Sekiguchi, Y Kaneko, M Sakurai, M Terada.   

Abstract

A DNA renaturation method in gel was used to detect amplified DNA fragments in eight gastric cancer cell lines, KATO-III, OKAJIMA, SCH, MKN1, MKN7, MKN28, MKN45 and MKN74 cells, and tissues of three metastases of gastric cancers to lymph nodes. There were amplified DNA sequences in three gastric cancer cell lines. Judging from the intensities of the bands, HindIII-digested DNA fragments were amplified several hundred times in the KATO-III and MKN7 cell lines. DNA from OKAJIMA cell line contained multiple bands with less intensity. KATO-III cells were found to contain a homogeneously staining region in chromosome 11.

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Year:  1986        PMID： 3095279

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  19 in total

1.  K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase.

Authors:  M Katoh; Y Hattori; H Sasaki; M Tanaka; K Sugano; Y Yazaki; T Sugimura; M Terada
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

2.  Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cells.

Authors:  S Imai; J Nishikawa; K Takada
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

3.  Epstein-Barr virus infection of human gastric carcinoma cells: implication of the existence of a new virus receptor different from CD21.

Authors:  H Yoshiyama; S Imai; N Shimizu; K Takada
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

4.  A new method for assaying adhesion of cancer cells to the greater omentum and its application for evaluating anti-adhesion activities of chemically synthesized oligosaccharides.

Authors:  A Okamura; S Yazawa; T Nishimura; S Tanaka; I Takai; S Kudo; T Asao; H Kuwano; K L Matta; S Akamatsu; N Kochibe
Journal:  Clin Exp Metastasis       Date:  2000       Impact factor: 5.150

5.  Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence.

Authors:  A K Walch; H F Zitzelsberger; J Bruch; G Keller; D Angermeier; M M Aubele; J Mueller; H Stein; H Braselmann; J R Siewert; H Höfler; M Werner
Journal:  Am J Pathol       Date:  2000-02       Impact factor: 4.307

Review 6.  Growth factors and oncogenes in human gastrointestinal carcinomas.

Authors:  E Tahara
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

7.  Induction of monocyte chemoattractant protein 1 by Helicobacter pylori involves NF-kappaB.

Authors:  N Mori; A Ueda; R Geleziunas; A Wada; T Hirayama; T Yoshimura; N Yamamoto
Journal:  Infect Immun       Date:  2001-03       Impact factor: 3.441

8.  Analysis of gene amplification in human tumor cell lines.

Authors:  M Fukumoto; D H Shevrin; I B Roninson
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

9.  A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiation.

Authors:  H Ishii; T Yoshida; H Oh; S Yoshida; M Terada
Journal:  Mol Cell Biol       Date:  1995-07       Impact factor: 4.272

10.  K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes.

Authors:  Y Hattori; H Odagiri; H Nakatani; K Miyagawa; K Naito; H Sakamoto; O Katoh; T Yoshida; T Sugimura; M Terada
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205
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