Literature DB >> 30952745

Extracorporeal Irradiation and Reimplantation of Tumor-bearing Bone Segments Following Diaphyseal Sarcoma Resection at the Tibia.

Andreas H Krieg1, Ulrich Lenze2, Leandra Schultze2, Markus W Gross3, Martin Haug4.   

Abstract

BACKGROUND/AIM: Reconstruction of diaphyseal tibial sarcomas with extracorporeal irradiated autograft is a rarely applied technique and is analyzed in this study. PATIENTS AND METHODS: Eight patients with malignant sarcomas received local treatment by means of a wide resection and reimplantation of an extracorporeally-irradiated autograft. The graft was combined with an ipsilateral vascularized fibula when a full-thickness segment of the tibia had to be resected and no cortex could be preserved (n=5). Oncological and functional results were recorded.
RESULTS: All patients had clear margins after resection, and with no local recurrence 72 months after treatment. Full weight-bearing was allowed at the time of radiological consolidation of the irradiated grafts (after a median of five months). The functional results were good and excellent in 7 of 8 patients, respectively.
CONCLUSION: Extracorporeal irradiation grafting is a suitable method for the treatment of localised and resectable tibial sarcomas. Copyright
© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Extracorporeal irradiation; diaphyseal tibial sarcomas; extracorporeally irradiated autograft; reimplantation; tumor-bearing bone segments

Mesh:

Year:  2019        PMID: 30952745     DOI: 10.21873/anticanres.13312

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  2 in total

Review 1.  [Specific intraoperative and secondary complications of biological reconstructions following extralesional tumour resections of malignant bone tumours].

Authors:  B Lehner; G W Omlor; A Geisbüsch; J Bollmann
Journal:  Orthopade       Date:  2020-02       Impact factor: 1.087

Review 2.  Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature.

Authors:  Filippo Migliorini; Gerardo La Padula; Ernesto Torsiello; Filippo Spiezia; Francesco Oliva; Nicola Maffulli
Journal:  Eur J Med Res       Date:  2021-10-02       Impact factor: 2.175

  2 in total

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