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Literature DB >> 30952447

Integrins and Their Role in Immune Cell Adhesion.

Abstract

One of the 2019 Canada Gairdner International Awards recognizes Timothy Springer's discovery of the first immune system adhesion molecules involved in lymphocyte homing and the translation of those discoveries into therapeutics for autoimmune disease and cancer.

Entities: Disease Species

Mesh：

Substances：

Year: 2019 PMID： 30952447 DOI： 10.1016/j.cell.2019.03.038

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

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Cited

18 in total

1. Phostensin enables lymphocyte integrin activation and population of peripheral lymphoid organs.

Authors: Ho-Sup Lee; Hao Sun; Frédéric Lagarrigue; Sarah Hyun Ji Kim; Jay W Fox; Nicholas E Sherman; Alexandre R Gingras; Mark H Ginsberg
Journal: J Exp Med Date: 2022-06-29 Impact factor: 17.579

2. Endothelial Dysfunction in the Context of Blood-Brain Barrier Modeling.

Authors: A G Kutikhin; D K Shishkova; E A Velikanova; M Yu Sinitsky; A V Sinitskaya; V E Markova
Journal: J Evol Biochem Physiol Date: 2022-06-29 Impact factor: 1.621

3. Transgenic overexpression of ITGB6 in intestinal epithelial cells exacerbates dextran sulfate sodium-induced colitis in mice.

Authors: Haiyan Chen; Liubo Chen; Xin Wang; Xiaoxu Ge; Lifeng Sun; Zhanhuai Wang; Xiaoming Xu; Yongmao Song; Jing Chen; Qun Deng; Haiting Xie; Ting Chen; Yan Chen; Kefeng Ding; Jingjing Wu; Jian Wang
Journal: J Cell Mol Med Date: 2021-01-24 Impact factor: 5.310

Integrins and Their Role in Immune Cell Adhesion.

1. Phostensin enables lymphocyte integrin activation and population of peripheral lymphoid organs.

2. Endothelial Dysfunction in the Context of Blood-Brain Barrier Modeling.

3. Transgenic overexpression of ITGB6 in intestinal epithelial cells exacerbates dextran sulfate sodium-induced colitis in mice.

Review 4. Surmounting the obstacles that impede effective CAR T cell trafficking to solid tumors.

Review 5. Natural Killer Cell Integrins and Their Functions in Tissue Residency.

6. Matrix Stiffness Modulates Mechanical Interactions and Promotes Contact between Motile Cells.

Review 7. Mechanistic Insight Into the Roles of Integrins in Osteoarthritis.

8. Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of Glioblastomas.

Review 9. Unraveling the mechanobiology of immune cells.

10. Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.