Literature DB >> 30951658

Toward a Universal Solution: Editing Compatibility into Pluripotent Stem Cells.

Alan Trounson1, Nicholas R Boyd2, Richard L Boyd2.   

Abstract

In this issue of Cell Stem Cell, Xu et al. (2019) demonstrate that editing iPSCs' major histocompatibility antigens may potentially provide a small set of universally compatible stem cell lines for therapies. However, these modifications may result in patient minor histocompatibility responses and deficiencies in their T cell response repertoire to infection and cancer.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2019        PMID: 30951658     DOI: 10.1016/j.stem.2019.03.003

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  5 in total

Review 1.  Immune and Genome Engineering as the Future of Transplantable Tissue.

Authors:  Jennifer Elisseeff; Stephen F Badylak; Jef D Boeke
Journal:  N Engl J Med       Date:  2021-12-23       Impact factor: 91.245

2.  Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing.

Authors:  Annie Kim; Kun-Gu Lee; Yeongbeen Kwon; Kang-In Lee; Heung-Mo Yang; Omer Habib; Jihun Kim; Sang-Tae Kim; Sung Joo Kim; Jin-Soo Kim; Dong-Youn Hwang
Journal:  Stem Cell Rev Rep       Date:  2021-01-09       Impact factor: 5.739

3.  Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy.

Authors:  Akram Al Abbar; Siew Ching Ngai; Nadine Nograles; Suleiman Yusuf Alhaji; Syahril Abdullah
Journal:  Biores Open Access       Date:  2020-04-28

4.  From genome editing to blastocyst complementation: A new horizon in heart transplantation?

Authors:  Igor E Konstantinov; Gregory King; Enzo R Porrello
Journal:  JTCVS Tech       Date:  2022-01-21

Review 5.  Diabetes Mellitus Is a Chronic Disease that Can Benefit from Therapy with Induced Pluripotent Stem Cells.

Authors:  Felipe Arroyave; Diana Montaño; Fernando Lizcano
Journal:  Int J Mol Sci       Date:  2020-11-18       Impact factor: 5.923

  5 in total

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