| Literature DB >> 30951418 |
Simona Gaito1, Christopher Hughes2, David Woolf3, Ganesh Radhakrishna3.
Abstract
This literature review clarifies the role of radiotherapy in the management of low-volume haemoptysis. Embase and Medline were interrogated, and PRISMA guidelines were then used to select relevant articles. Seventy-eight articles were considered relevant and manually reviewed. The evidence suggests that external beam radiotherapy is more effective than endobronchial brachytherapy at controlling low-volume haemoptysis. There is no evidence to recommend a combination of the two techniques. Different doses and fractionations appear equally effective, with a potential survival advantage of higher dose regimens for fitter patients. Palliative radiotherapy is effective at controlling low-volume haemoptysis. External beam radiotherapy is the first-line treatment, with endobronchial brachytherapy recommended following external beam radiotherapy failure. Choice of dose and fractionation should take into account the patient's performance status.Entities:
Mesh:
Year: 2019 PMID: 30951418 DOI: 10.12968/hmed.2019.80.4.211
Source DB: PubMed Journal: Br J Hosp Med (Lond) ISSN: 1750-8460 Impact factor: 0.825