| Literature DB >> 3094941 |
Z Bartoszewicz, J Kościelak, T Pacuszka.
Abstract
A major mono- and a di-sialoganglioside were isolated and purified to homogeneity from a spontaneous thymoma that occurs in AKR mice. Compositional and methylation analyses and the use of exoglycosidases established the monosialoganglioside to be alpha Neu(2----3)beta Gal(1----3)beta GalNAc(1----4)beta Gal(1----4)Glc(1----4)Cer and the disialoganglioside to be alpha NeuAc(2----8)alpha NeuAc(2----3)beta Gal(1----3)beta GalNAc(1----4)beta Gal(1----4)Glc(1----1)Cer (GD1c). A possible pathway for the biosynthesis of this disialoganglioside is presented.Entities:
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Year: 1986 PMID： 3094941 DOI： 10.1016/s0008-6215(00)90331-8
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104