Literature DB >> 30947537

The protective role of carnosic acid in ischemic/reperfusion injury through regulation of autophagy under T2DM.

Min Hu1, Tianyu Li1, Zixiang Bo1, Feixiang Xiang2,3.   

Abstract

IMPACT STATEMENT: We have provided, for the first time, evidence that carnosic acid (CA) attenuates ischemia-reperfusion injury of diabetic myocardium, i.e. diabetic myocardial ischemia/reperfusion (DMI/R) injury, via enhancement of autophagy. A greater understanding of the target molecule in CA-enhanced autophagy is necessary for the development of potential chemotherapy for DMI/R injury.

Entities:  

Keywords:  Autophagy; apoptosis; carnosic acid; diabetes mellitus; inflammation; myocardial ischemia/reperfusion

Mesh：

Substances：

Year:  2019        PMID： 30947537      PMCID： PMC6545691          DOI： 10.1177/1535370219840987

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN： 1535-3699


  51 in total

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Authors:  Wolfgang Rathmann; Guido Giani
Journal:  Diabetes Care       Date:  2004-10       Impact factor: 19.112

2.  FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions.

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Journal:  Nat Rev Mol Cell Biol       Date:  2005-11       Impact factor: 94.444

4.  Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

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Journal:  Biochem J       Date:  1999-12-01       Impact factor: 3.857

5.  Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin.

Authors:  Giuseppe Petrosillo; Francesca M Ruggiero; Nicola Di Venosa; Giuseppe Paradies
Journal:  FASEB J       Date:  2003-02-05       Impact factor: 5.191

6.  Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

Authors:  Thomas Thom; Nancy Haase; Wayne Rosamond; Virginia J Howard; John Rumsfeld; Teri Manolio; Zhi-Jie Zheng; Katherine Flegal; Christopher O'Donnell; Steven Kittner; Donald Lloyd-Jones; David C Goff; Yuling Hong; Robert Adams; Gary Friday; Karen Furie; Philip Gorelick; Brett Kissela; John Marler; James Meigs; Veronique Roger; Stephen Sidney; Paul Sorlie; Julia Steinberger; Sylvia Wasserthiel-Smoller; Matthew Wilson; Philip Wolf
Journal:  Circulation       Date:  2006-01-11       Impact factor: 29.690

7.  Induction of autophagy and inhibition of tumorigenesis by beclin 1.

Authors:  X H Liang; S Jackson; M Seaman; K Brown; B Kempkes; H Hibshoosh; B Levine
Journal:  Nature       Date:  1999-12-09       Impact factor: 49.962

8.  Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1,25-dihydroxyvitamin D3 and retinoic acid.

Authors:  M Steiner; I Priel; J Giat; J Levy; Y Sharoni; M Danilenko
Journal:  Nutr Cancer       Date:  2001       Impact factor: 2.900

9.  Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion.

Authors:  Stephan Baldus; Thomas Heitzer; Jason P Eiserich; Denise Lau; Hanke Mollnau; Michelle Ortak; Susan Petri; Britta Goldmann; Hans-Jürgen Duchstein; Jürgen Berger; Udo Helmchen; Bruce A Freeman; Thomas Meinertz; Thomas Münzel
Journal:  Free Radic Biol Med       Date:  2004-09-15       Impact factor: 7.376

10.  LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.

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Journal:  J Cell Sci       Date:  2004-06-01       Impact factor: 5.285
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  2 in total

1.  Effect of Rho-Kinase and Autophagy on Remote Ischemic Conditioning-Induced Cardioprotection in Rat Myocardial Ischemia/Reperfusion Injury Model.

Authors:  Jie Gao; Feng Min; Shasha Wang; Heng Lv; Huan Liang; Ben Cai; Xianjie Jia; Qin Gao; Ying Yu
Journal:  Cardiovasc Ther       Date:  2022-01-06       Impact factor: 3.023

2.  Protective Effects of Carnosic Acid on Lipopolysaccharide-Induced Acute Kidney Injury in Mice.

Authors:  Jung-Yeon Kim; Hyo-Lim Hong; Gyun Moo Kim; Jaechan Leem; Hyun Hee Kwon
Journal:  Molecules       Date:  2021-12-14       Impact factor: 4.411
  2 in total

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