Ruth T Morin1, Craig Nelson2, David Bickford2, Philip S Insel3,4, R Scott Mackin1,2,3. 1. Mental Health Service, San Francisco VA Medical Center, San Francisco, California, USA. 2. Department of Psychiatry, University of California San Francisco, San Francisco, California, USA. 3. San Francisco VA Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, USA. 4. Faculty of Medicine, Clinical Memory Research Unit, Lund University, Lund, Sweden.
Abstract
Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression.Method: Data were analyzed from 78 older adults aged 65-88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of these symptoms. Other symptoms of depression were also assessed using the remaining items of the HDRS. Current physical health burden was assessed using the Functional Comorbidity Index (FCI). Disability was measured with the Late Life Function and Disability Instrument (LLFDI) total limitation score. A linear regression analysis was performed to assess the association of somatic and anxiety symptoms with disability independent of other factors. Results: The model accounted for 26.6% of variance in disability, (F(6,51) = 3.1, p = .01). Somatic (B = -1.9, p = .004) and anxiety (B = -3.7, p = .04) symptoms of depression were significantly associated with disability. Other depressive symptoms and physical illness burden were not associated with disability.Discussion: In older adults with major depression, somatic and anxiety symptoms of depression are associated with disability. Identification and treatment to remission of these symptoms may improve functional outcomes among older depressed adults.
Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression.Method: Data were analyzed from 78 older adults aged 65-88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of these symptoms. Other symptoms of depression were also assessed using the remaining items of the HDRS. Current physical health burden was assessed using the Functional Comorbidity Index (FCI). Disability was measured with the Late Life Function and Disability Instrument (LLFDI) total limitation score. A linear regression analysis was performed to assess the association of somatic and anxiety symptoms with disability independent of other factors. Results: The model accounted for 26.6% of variance in disability, (F(6,51) = 3.1, p = .01). Somatic (B = -1.9, p = .004) and anxiety (B = -3.7, p = .04) symptoms of depression were significantly associated with disability. Other depressive symptoms and physical illness burden were not associated with disability.Discussion: In older adults with major depression, somatic and anxiety symptoms of depression are associated with disability. Identification and treatment to remission of these symptoms may improve functional outcomes among older depressed adults.
Entities:
Keywords:
Late life depression; anxious symptoms; disability; somatic symptoms
Authors: R C Kessler; N A Sampson; P Berglund; M J Gruber; A Al-Hamzawi; L Andrade; B Bunting; K Demyttenaere; S Florescu; G de Girolamo; O Gureje; Y He; C Hu; Y Huang; E Karam; V Kovess-Masfety; S Lee; D Levinson; M E Medina Mora; J Moskalewicz; Y Nakamura; F Navarro-Mateu; M A Oakley Browne; M Piazza; J Posada-Villa; T Slade; M Ten Have; Y Torres; G Vilagut; M Xavier; Z Zarkov; V Shahly; M A Wilcox Journal: Epidemiol Psychiatr Sci Date: 2015-02-27 Impact factor: 6.892
Authors: Jordan F Karp; Elizabeth Skidmore; Meredith Lotz; Eric Lenze; Mary Amanda Dew; Charles F Reynolds Journal: J Am Geriatr Soc Date: 2009-07-21 Impact factor: 5.562
Authors: David Bickford; Ruth T Morin; Cara Woodworth; Elizabeth Verduzco; Maryam Khan; Emily Burns; J Craig Nelson; R Scott Mackin Journal: Aging Ment Health Date: 2019-12-06 Impact factor: 3.658
Authors: Suzaily Wahab; Tien Yong Chua; Rosdinom Razali; Zanariah Mat Saher; Iman Hakimi Zamzam; Mohamad Adam Bujang Journal: Psychol Res Behav Manag Date: 2022-03-24