| Literature DB >> 3094437 |
E Yourassowsky, M P Van der Linden, M J Lismont, F Crokaert, Y Glupczynski.
Abstract
The rate of bactericidal activity of a new quinolone, CI-934, was compared with that of amoxicillin for 20 strains of Streptococcus faecalis. At 10 and 100 micrograms/ml, the bactericidal activity of CI-934 was more rapid at 6 h than that of amoxicillin. A paradoxical effect (a killing rate higher at 1 microgram/ml than at 100 micrograms/ml at 6 h) was observed for 19 of the 20 strains with amoxicillin and for 1 of the 20 strains with CI-934. It remains to be demonstrated whether in vivo studies will confirm the results obtained in vitro.Entities:
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Year: 1986 PMID: 3094437 PMCID: PMC180530 DOI: 10.1128/AAC.30.2.258
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191