Literature DB >> 3094411

Protective effect of disodium cromoglycate on allergen-induced bronchoconstriction and increased hyperresponsiveness: a double-blind placebo-controlled study.

S Mattoli, A Foresi, G M Corbo, G Polidori, G Ciappi.   

Abstract

The protective effect of 40 mg cromolyn on allergen-induced late response and increased hyperresponsiveness were studied in five asthmatic children to whom this drug and saline placebo were administered 20 minutes before allergen inhalation, at random, double-blind. Cromolyn reduced the magnitude of early and late responses and abolished the increase in methacholine responsiveness.

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Year:  1986        PMID: 3094411

Source DB:  PubMed          Journal:  Ann Allergy        ISSN: 0003-4738


  2 in total

Review 1.  The pharmacology of airway hyperresponsiveness and inflammation.

Authors:  R Pauwels
Journal:  Lung       Date:  1990       Impact factor: 2.584

2.  Cromoglycate and nedocromil: influence on airway reactivity.

Authors:  E A Valletta; A L Boner
Journal:  Mediators Inflamm       Date:  1994       Impact factor: 4.711

  2 in total

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