| Literature DB >> 30943861 |
Tarek Assi1, Alina Danu1, Christine Mateus2, Caroline Robert2, Jean-Marie Michot1,3, Tony Ibrahim1, Julien Lazarovici1, David Ghez1, Julien Rossignol1, Peggy Dartigues4, Marie Terroir-Cassou-Mounat5, Vincent Ribrag1,3.
Abstract
The most recent progress in the oncology field has led to a paradigm shift in the management of cancer with the tsunami of immune checkpoint inhibitors that are associated with a particular pattern of immunological adverse events. This is a case of a 54-year-old woman that demonstrated a granulomatous reaction in the same dermatomal distribution of a previously treated shingles infection during treatment with an anti-programmed death 1 agent (pembrolizumab) for a newly diagnosed stage IV Hodgkin lymphoma. The purpose of this case is to increase the awareness of oncologists dealing with a new pattern of side effects taking into account the patient's background and recent exposures to latent viruses such as herpes zoster to prevent unnecessary diagnostic and therapeutic measures.Entities:
Keywords: Hodgkin lymphoma; Immune granulomatosis; immune checkpoint inhibitors; pembrolizumab; shingles
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Year: 2019 PMID: 30943861 DOI: 10.2217/imt-2018-0169
Source DB: PubMed Journal: Immunotherapy ISSN: 1750-743X Impact factor: 4.196