Literature DB >> 30943861

Post-shingles granulomatous dermatosis related to anti-programmed cell death 1.

Tarek Assi1, Alina Danu1, Christine Mateus2, Caroline Robert2, Jean-Marie Michot1,3, Tony Ibrahim1, Julien Lazarovici1, David Ghez1, Julien Rossignol1, Peggy Dartigues4, Marie Terroir-Cassou-Mounat5, Vincent Ribrag1,3.   

Abstract

The most recent progress in the oncology field has led to a paradigm shift in the management of cancer with the tsunami of immune checkpoint inhibitors that are associated with a particular pattern of immunological adverse events. This is a case of a 54-year-old woman that demonstrated a granulomatous reaction in the same dermatomal distribution of a previously treated shingles infection during treatment with an anti-programmed death 1 agent (pembrolizumab) for a newly diagnosed stage IV Hodgkin lymphoma. The purpose of this case is to increase the awareness of oncologists dealing with a new pattern of side effects taking into account the patient's background and recent exposures to latent viruses such as herpes zoster to prevent unnecessary diagnostic and therapeutic measures.

Entities:  

Keywords:  Hodgkin lymphoma; Immune granulomatosis; immune checkpoint inhibitors; pembrolizumab; shingles

Mesh:

Substances:

Year:  2019        PMID: 30943861     DOI: 10.2217/imt-2018-0169

Source DB:  PubMed          Journal:  Immunotherapy        ISSN: 1750-743X            Impact factor:   4.196


  3 in total

1.  Herpes zoster granulomatous dermatitis in metastatic lung cancer treated with nivolumab: A case report.

Authors:  Elisa Gozzi; Luigi Rossi; Francesco Angelini; Valentina Leoni; Patrizia Trenta; Giuseppe Cimino; Silverio Tomao
Journal:  Thorac Cancer       Date:  2020-03-05       Impact factor: 3.500

2.  Do checkpoint inhibitors compromise the cancer patients' immunity and increase the vulnerability to COVID-19 infection?

Authors:  Joseph Kattan; Clarisse Kattan; Tarek Assi
Journal:  Immunotherapy       Date:  2020-04-14       Impact factor: 4.196

Review 3.  Infections due to dysregulated immunity: an emerging complication of cancer immunotherapy.

Authors:  Tommaso Morelli; Kohei Fujita; Gil Redelman-Sidi; Paul T Elkington
Journal:  Thorax       Date:  2021-10-04       Impact factor: 9.139

  3 in total

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