Literature DB >> 30942238

A lysosome-targeting and polarity-specific fluorescent probe for cancer diagnosis.

Li Fan1, Xiaodong Wang, Jinyin Ge, Feng Li, Xiao Wang, Juanjuan Wang, Shaomin Shuang, Chuan Dong.   

Abstract

A lysosome-targeting and polarity-specific fluorescent probe CPM has been rationally designed for cancer diagnosis and imaging. We have successfully shown that lysosome polarity may serve as an ubiquitious marker for cancer detection. The potential of CPM for cancer diagnosis has also been demonstrated at the levels of live cells, organs, whole animal, and clinical patient tissue samples.

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Year:  2019        PMID： 30942238     DOI： 10.1039/c9cc00962k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.

Authors:  Joana Krämer; Rui Kang; Laura M Grimm; Luisa De Cola; Pierre Picchetti; Frank Biedermann
Journal:  Chem Rev       Date:  2022-01-07       Impact factor: 60.622

2.  Building Accurate Intracellular Polarity Maps through Multiparametric Microscopy.

Authors:  M Carmen Gonzalez-Garcia; Pilar Herrero-Foncubierta; Emilio Garcia-Fernandez; Angel Orte
Journal:  Methods Protoc       Date:  2020-11-11

3.  Strategic engineering of alkyl spacer length for a pH-tolerant lysosome marker and dual organelle localization.

Authors:  Suprakash Biswas; Tanoy Dutta; Akshay Silswal; Rohit Bhowal; Deepak Chopra; Apurba L Koner
Journal:  Chem Sci       Date:  2021-06-14       Impact factor: 9.825

4.  Combining hydrophilic and hydrophobic environment sensitive dyes to detect a wide range of cellular polarity.

Authors:  Sang Jun Park; Vinayak Juvekar; Jae Hyung Jo; Hwan Myung Kim
Journal:  Chem Sci       Date:  2019-11-25       Impact factor: 9.825
  4 in total

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