| Literature DB >> 30939001 |
Andrew C Flick1, Carolyn A Leverett2, Hong X Ding3, Emma McInturff2, Sarah J Fink4, Christopher J Helal2, Christopher J O'Donnell2.
Abstract
New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 31 new chemical entities approved for the first time globally in 2017.Mesh：
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Year: 2019 PMID： 30939001 DOI： 10.1021/acs.jmedchem.9b00196
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446