Literature DB >> 30937863

Pericytes in Skeletal Muscle.

Jyoti Gautam1, Yao Yao2.   

Abstract

Skeletal muscle regeneration is a highly orchestrated process and involves the activation of many cellular and molecular pathways. Although satellite cells (SCs) are the major cell type responsible for muscle regeneration, pericytes show remarkable myogenic potential and various advantages as cell therapy in muscular disorders. This chapter first introduces the structure, marker expression, origin, and category of pericytes. Next, we discuss their functions in muscular dystrophy and/or muscle injuries, focusing on their myogenic, adipogenic, fibrogenic, chondrogenic, and osteogenic activities. Understanding this knowledge will promote the development of innovative cell therapies for muscle disorders, including muscular dystrophy.

Entities:  

Keywords:  Adipogenesis; Chondrogenesis; Differentiation; Fibrosis; Mesoangioblasts; Muscle injury; Muscle regeneration; Muscular dystrophy; Myogenesis; Ossification; Osteogenesis; Pericytes; Satellite cells

Mesh:

Year:  2019        PMID: 30937863     DOI: 10.1007/978-3-030-11093-2_4

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

Review 1.  The Survey of Cells Responsible for Heterotopic Ossification Development in Skeletal Muscles-Human and Mouse Models.

Authors:  Łukasz Pulik; Bartosz Mierzejewski; Maria A Ciemerych; Edyta Brzóska; Paweł Łęgosz
Journal:  Cells       Date:  2020-05-26       Impact factor: 6.600

  1 in total

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