| Literature DB >> 30935717 |
Jennifer Taylor Veneris1, Elizabeth K Lee2, Emily A Goebel3, Marisa R Nucci4, Neal Lindeman5, Neil S Horowitz6, Larissa Lee7, Chandrajit P Raut8, David Crotzer9, Ursula Matulonis10, Panagiotis A Konstantinopoulos10, Susana Campos10.
Abstract
Polymerase-epsilon (POLE)-mutated carcinomas are a rare, but well-known subtype of endometrial cancer. While typically associated with good prognosis, recurrences are documented. Here we present a case of recurrent POLE-mutated endometrial cancer, discuss pathologic features, current methods of molecular classification, and explore therapeutic implications for the POLE-mutation phenotype.Entities:
Mesh：
Substances：
Year: 2019 PMID： 30935717 DOI： 10.1016/j.ygyno.2019.03.247
Source DB: PubMed Journal: Gynecol Oncol ISSN： 0090-8258 Impact factor: 5.482