| Literature DB >> 30935573 |
Stéphane Supiot1, Caroline Rousseau2, Mélanie Dore2, Catherine Chèze-Le-Rest3, Christine Kandel-Aznar4, Vincent Potiron2, Stéphane Guerif3, François Paris2, Ludovic Ferrer2, Loïc Campion2, Philippe Meingan5, Grégory Delpon2, Mathieu Hatt6, Dimitris Visvikis6.
Abstract
Hypoxia is a major risk factor of prostate cancer radioresistance. We evaluated hypoxia non-invasively, using 18F-Misonidazole PET/CT prior to radiotherapy and after a dose of 20 Gy in intermediate-risk prostate cancer patients. Decreased hypoxic volumes were observed in all patients, suggesting that radiotherapy induces early prostate tumor reoxygenation.Entities:
Keywords: Dose painting radiotherapy; FAZA; IMRT; Misonidazole; Radioresistance
Year: 2019 PMID: 30935573 DOI: 10.1016/j.radonc.2018.12.022
Source DB: PubMed Journal: Radiother Oncol ISSN: 0167-8140 Impact factor: 6.280