Ming-Hsien Yeh1, Chiu-Hui Chao2, Malcolm Koo3, Chiu-Yuan Chen4, Chia-Chou Yeh5, Te-Mao Li6. 1. Graduate Institute of Chinese Medicine, China Medical University, Taichung City 40402, Taiwan; Department of Chinese Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Chiayi 62247, Taiwan. 2. Graduate Institute of Chinese Medicine, China Medical University, Taichung City 40402, Taiwan. 3. Graduate Institute of Long-Term Care, Tzu Chi University of Science and Technology, Hualien City, Hualien 97005, Taiwan; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario M5T 3M7, Canada. 4. Department of Natural Biotechnology, Nanhua University, Dalin, Chiayi 62249, Taiwan. 5. Department of Chinese Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Chiayi 62247, Taiwan; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien City, Hualien 97004, Taiwan. Electronic address: yehcc0530@gmail.com. 6. Graduate Institute of Chinese Medicine, China Medical University, Taichung City 40402, Taiwan. Electronic address: leedemaw@mail.cmu.edu.tw.
Abstract
BACKGROUND AND PURPOSE: Fatigue is one of the most prevalent adverse events reported by cancer patients. The aim of this study was to investigate the association between traditional Chinese medicine body constitution (TCMBC) and moderate-to-severe cancer-related fatigue in cancer patients. MATERIALS AND METHODS: A cross-sectional study was conducted on cancer patients recruited from a regional hospital in southern Taiwan. The association between TCMBC, measured using the Constitution in Chinese Medicine Questionnaire (CCMQ) and moderate-to-severe cancer-related fatigue (based on the Taiwanese version of the Brief Fatigue Inventory score ≥ 4) was evaluated using multiple logistic regression analysis. RESULTS: Of the 170 participants, 37 (21.8%) had moderate-to-severe fatigue. Yang-deficiency (adjusted odds ratio [aOR] = 3.55, 95% confidence interval [CI] = 1.50-8.40) and Qi-deficiency (aOR = 2.84, 95% CI = 1.18-6.82) TCMBC were significantly associated with moderate-to-severe cancer-related fatigue. CONCLUSION: TCMBC could be used as a clinical tool to identify cancer patients prone to experience moderate-to-severe cancer-related fatigue, and to provide Chinese medicine practitioners a basis for selecting an appropriate treatment approach based on TCMBC.
BACKGROUND AND PURPOSE:Fatigue is one of the most prevalent adverse events reported by cancerpatients. The aim of this study was to investigate the association between traditional Chinese medicine body constitution (TCMBC) and moderate-to-severe cancer-related fatigue in cancerpatients. MATERIALS AND METHODS: A cross-sectional study was conducted on cancerpatients recruited from a regional hospital in southern Taiwan. The association between TCMBC, measured using the Constitution in Chinese Medicine Questionnaire (CCMQ) and moderate-to-severe cancer-related fatigue (based on the Taiwanese version of the Brief Fatigue Inventory score ≥ 4) was evaluated using multiple logistic regression analysis. RESULTS: Of the 170 participants, 37 (21.8%) had moderate-to-severe fatigue. Yang-deficiency (adjusted odds ratio [aOR] = 3.55, 95% confidence interval [CI] = 1.50-8.40) and Qi-deficiency (aOR = 2.84, 95% CI = 1.18-6.82) TCMBC were significantly associated with moderate-to-severe cancer-related fatigue. CONCLUSION:TCMBC could be used as a clinical tool to identify cancerpatients prone to experience moderate-to-severe cancer-related fatigue, and to provide Chinese medicine practitioners a basis for selecting an appropriate treatment approach based on TCMBC.
Authors: Jing-Yu Benjamin Tan; Tao Wang; Isabella Zhao; Mary Janice Polotan; Sabina Eliseeva Journal: Int J Environ Res Public Health Date: 2022-09-21 Impact factor: 4.614