Literature DB >> 30931723

Constructing Matched Groups in Dental Observational Health Disparity Studies for Causal Effects.

J Cheng1,2, S E Gregorich1,2,3, S A Gansky1,2,4,5, S A Fisher-Owens2,6, A M Kottek2,4, J M White1,2, E A Mertz1,2,4.   

Abstract

INTRODUCTION: Electronic health record (EHR) systems provide investigators with rich data from which to examine actual impacts of care delivery in real-world settings. However, confounding is a major concern when comparison groups are not randomized.
OBJECTIVES: This article introduced a step-by-step strategy to construct comparable matched groups in a dental study based on the EHR of the Willamette Dental Group. This strategy was employed in preparation for a longitudinal study evaluating the impact of a standardized risk-based caries prevention and management program across patients with public versus private dental insurance in Oregon.
METHODS: This study constructed comparable dental patient groups through a process of 1) evaluating the need for and feasibility of matching, 2) considering different matching methods, and 3) evaluating matching quality. The matched groups were then compared for their average ratio in the number of decayed, missing, and filled tooth surfaces (DMFS + dmfs) at baseline.
RESULTS: This systematic process resulted in comparably matched groups in baseline covariates but with a clear baseline disparity in caries experience between them. The weighted average ratio in our study showed that, at baseline, publicly insured patients had 1.21-times (95% CI: 1.08 to 1.32) and 1.21-times (95% CI: 1.08 to 1.37) greater number of DMFS + dmfs and number of decayed tooth surfaces (DS + ds) than privately insured patients, respectively.
CONCLUSION: Matching is a useful tool to create comparable groups with EHR data to resemble randomized studies, as demonstrated by our study where even with similar demographics, neighborhood and clinic characteristics, publicly insured pediatric patients had greater numbers of DMFS + dmfs and DS + ds than privately insured pediatric patients. KNOWLEDGE TRANSFER STATEMENT: This article provides a systematic, step-by-step strategy for investigators to follow when matching groups in a study-in this case, a study based on electronic health record data. The results from this study will provide patients, clinicians, and policy makers with information to better understand the disparities in oral health between comparable publicly and privately insured pediatric patients who have similar values in individual, clinic, and community covariates. Such understanding will help clinicians and policy makers modify oral health care and relevant policies to improve oral health and reduce disparities between publicly and privately insured patients.

Entities:  

Keywords:  caries management; electronic health record; health equity; matching; observational cohort study; propensity score

Mesh:

Year:  2019        PMID: 30931723      PMCID: PMC6918038          DOI: 10.1177/2380084419830655

Source DB:  PubMed          Journal:  JDR Clin Trans Res        ISSN: 2380-0844


  12 in total

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2.  Attributes of an ideal oral health care system.

Authors:  Scott L Tomar; Lois K Cohen
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3.  The design versus the analysis of observational studies for causal effects: parallels with the design of randomized trials.

Authors:  Donald B Rubin
Journal:  Stat Med       Date:  2007-01-15       Impact factor: 2.373

4.  Developing practical recommendations for the use of propensity scores: discussion of 'A critical appraisal of propensity score matching in the medical literature between 1996 and 2003' by Peter Austin, Statistics in Medicine.

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Journal:  Stat Med       Date:  2008-05-30       Impact factor: 2.373

5.  Matching using estimated propensity scores: relating theory to practice.

Authors:  D B Rubin; N Thomas
Journal:  Biometrics       Date:  1996-03       Impact factor: 2.571

Review 6.  Instrumental variable methods in comparative safety and effectiveness research.

Authors:  M Alan Brookhart; Jeremy A Rassen; Sebastian Schneeweiss
Journal:  Pharmacoepidemiol Drug Saf       Date:  2010-06       Impact factor: 2.890

7.  The effectiveness of adjustment by subclassification in removing bias in observational studies.

Authors:  W G Cochran
Journal:  Biometrics       Date:  1968-06       Impact factor: 2.571

Review 8.  Organizing care for patients with chronic illness.

Authors:  E H Wagner; B T Austin; M Von Korff
Journal:  Milbank Q       Date:  1996       Impact factor: 4.911

9.  Average causal effects from nonrandomized studies: a practical guide and simulated example.

Authors:  Joseph L Schafer; Joseph Kang
Journal:  Psychol Methods       Date:  2008-12

10.  Influences on children's oral health: a conceptual model.

Authors:  Susan A Fisher-Owens; Stuart A Gansky; Larry J Platt; Jane A Weintraub; Mah-J Soobader; Matthew D Bramlett; Paul W Newacheck
Journal:  Pediatrics       Date:  2007-09       Impact factor: 9.703

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  1 in total

1.  Caries Risk Documentation And Prevention: eMeasures For Dental Electronic Health Records.

Authors:  Suhasini Bangar; Ana Neumann; Joel M White; Alfa Yansane; Todd R Johnson; Gregory W Olson; Shwetha V Kumar; Krishna K Kookal; Aram Kim; Enihomo Obadan-Udoh; Elizabeth Mertz; Kristen Simmons; Joanna Mullins; Ryan Brandon; Muhammad F Walji; Elsbeth Kalenderian
Journal:  Appl Clin Inform       Date:  2022-01-19       Impact factor: 2.342

  1 in total

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