Literature DB >> 30931466

Head to tail cyclisation of cell-penetrating peptides: impact on GAG-dependent internalisation and direct translocation.

Mehdi Amoura1, Françoise Illien, Alain Joliot, Karine Guitot, John Offer, Sandrine Sagan, Fabienne Burlina.   

Abstract

A series of cyclic lipidated oligo-Arg cell penetrating peptides were synthesised with varied macrocycle size and lipid chain anchoring site. The study of their cellular uptake revealed different structural requirements to promote efficient glycosaminoglycan-dependent endocytosis and direct translocation.

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Year:  2019        PMID： 30931466     DOI： 10.1039/c9cc01265f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Cyclic Cell-Penetrating Peptides with Single Hydrophobic Groups.

Authors:  Jian Song; Ziqing Qian; Ashweta Sahni; Kuangyu Chen; Dehua Pei
Journal:  Chembiochem       Date:  2019-07-24       Impact factor: 3.164

2.  Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction.

Authors:  Heba Salim; Jian Song; Ashweta Sahni; Dehua Pei
Journal:  J Org Chem       Date:  2019-10-28       Impact factor: 4.354

3.  Discovery of a Cyclic Cell-Penetrating Peptide with Improved Endosomal Escape and Cytosolic Delivery Efficiency.

Authors:  Marina Buyanova; Ashweta Sahni; Rui Yang; Amar Sarkar; Heba Salim; Dehua Pei
Journal:  Mol Pharm       Date:  2022-04-11       Impact factor: 5.364

Review 4.  Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System.

Authors:  Ildikó Szabó; Mo'ath Yousef; Dóra Soltész; Csaba Bató; Gábor Mező; Zoltán Bánóczi
Journal:  Pharmaceutics       Date:  2022-04-21       Impact factor: 6.525

5.  Engineering Cell-Permeable Proteins through Insertion of Cell-Penetrating Motifs into Surface Loops.

Authors:  Kuangyu Chen; Dehua Pei
Journal:  ACS Chem Biol       Date:  2020-08-20       Impact factor: 5.100

6.  Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides.

Authors:  Ildikó Szabó; Françoise Illien; Levente E Dókus; Mo'ath Yousef; Zsuzsa Baranyai; Szilvia Bősze; Shoko Ise; Kenichi Kawano; Sandrine Sagan; Shiroh Futaki; Ferenc Hudecz; Zoltán Bánóczi
Journal:  Amino Acids       Date:  2021-05-25       Impact factor: 3.520

7.  Sulfated Glycoaminoglycans and Proteoglycan Syndecan-4 Are Involved in Membrane Fixation of LL-37 and Its Pro-Migratory Effect in Breast Cancer Cells.

Authors:  Chahrazed Habes; Günther Weber; Caroline Goupille
Journal:  Biomolecules       Date:  2019-09-12
  7 in total

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