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Literature DB >> 3093033

Treatment of psoriasis vulgaris by oral administration of 1 alpha-hydroxyvitamin D3--open-design study.

S Morimoto, K Yoshikawa, T Kozuka, Y Kitano, S Imanaka, K Fukuo, E Koh, T Onishi, Y Kumahara.

Abstract

In an open-design study 1 alpha-hydroxyvitamin D3 was administered orally to 17 patients with psoriasis vulgaris at a dose of 1.0 micrograms/day for 6 months. More than moderate improvement was observed in 13 (76%) of the 17 patients from 2.7 +/- 0.6 months (mean +/- SD) after the start of treatment. No side effects of the treatment were observed. The mechanism of the effect of 1 alpha-hydroxyvitamin D3 requires study, but these data suggest that its oral administration is effective for treatment of psoriasis vulgaris.

Entities: Chemical Disease Species

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Year: 1986 PMID： 3093033 DOI： 10.1007/bf02555120

Source DB: PubMed Journal: Calcif Tissue Int ISSN： 0171-967X Impact factor: 4.333

21 in total

1. Metabolism of 1alpha-hydroxyvitamin D3 to 1alpha, 25-dihydroxyvitamin D3 in perfused rat liver.

Authors: M Fukushima; Y Suzuki; Y Toira; I Matsunaga; K Ochi; H Nagano
Journal: Biochem Biophys Res Commun Date: 1975-09-16 Impact factor: 3.575

2. A convenient synthesis of 1 -hydroxy-vitamin D 3 .

Authors: D H Barton; R H Hesse; M M Pechet; E Rizzardo
Journal: J Am Chem Soc Date: 1973-04-18 Impact factor: 15.419

3. Psoriasis exacerbated by hypoparathyroidism with hypocalcaemia.

Authors: G Risum
Journal: Br J Dermatol Date: 1973-09 Impact factor: 9.302

4. Abnormal cell proliferation in psoriasis.

Authors: G D Weinstein; P Frost
Journal: J Invest Dermatol Date: 1968-03 Impact factor: 8.551

5. 1 alpha,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells.

Authors: C Miyaura; E Abe; T Kuribayashi; H Tanaka; K Konno; Y Nishii; T Suda
Journal: Biochem Biophys Res Commun Date: 1981-10-15 Impact factor: 3.575

6. Normal serum 1,25-dihydroxyvitamin D in patients with medullary carcinoma of the thyroid.

Authors: S Lee; S Morimoto; T Onishi; M Tsuji; Y Okada; Y Seino; M Ishida; K Yamaoka; S Takai; A Miyauchi; Y Kumahara
Journal: J Clin Endocrinol Metab Date: 1982-08 Impact factor: 5.958

7. Characterization of a receptor-like protein for 1,25-dihydroxyvitamin D3 in rat skin.

Authors: R U Simpson; H F DeLuca
Journal: Proc Natl Acad Sci U S A Date: 1980-10 Impact factor: 11.205

8. Demonstration of 1,25-dihydroxyvitamin D3 receptors in human skin biopsies.

Authors: D Feldman; T Chen; M Hirst; K Colston; M Karasek; C Cone
Journal: J Clin Endocrinol Metab Date: 1980-12 Impact factor: 5.958

9. The effect of oestrogens on human calcitonin secretion after calcium infusion in elderly female subjects.

Authors: S Morimoto; M Tsuji; Y Okada; T Onishi; Y Kumahara
Journal: Clin Endocrinol (Oxf) Date: 1980-08 Impact factor: 3.478

10. Cultured psoriatic fibroblasts from involved and uninvolved sites have a partial but not absolute resistance to the proliferation-inhibition activity of 1,25-dihydroxyvitamin D3.

Authors: J A MacLaughlin; W Gange; D Taylor; E Smith; M F Holick
Journal: Proc Natl Acad Sci U S A Date: 1985-08 Impact factor: 11.205

4 in total

Review 4. Nutrition and Psoriasis.

Authors: Naoko Kanda; Toshihiko Hoashi; Hidehisa Saeki
Journal: Int J Mol Sci Date: 2020-07-29 Impact factor: 5.923