Corina de Graaf1, Stefanie G Beesems2, Rudolph W Koster2. 1. Amsterdam UMC, Academic Medical Center, Heart Center, Department of Cardiology, Meibergdreef 9, Amsterdam, The Netherlands. Electronic address: c.degraaf@amc.uva.nl. 2. Amsterdam UMC, Academic Medical Center, Heart Center, Department of Cardiology, Meibergdreef 9, Amsterdam, The Netherlands.
Abstract
BACKGROUND: In out-of-hospital cardiac arrest (OHCA), return of spontaneous circulation (ROSC) on scene occurs only in a minority of patients. The optimal duration of resuscitation on scene before transport with ongoing cardiopulmonary resuscitation (CPR) is unknown. PURPOSE: To determine the time of resuscitation on scene ('time on scene') and survival in patients transported with ongoing CPR in the Netherlands. METHODS: Data on OHCA patients (>18 years) without ROSC on scene, where resuscitation was started between January 1, 2012 and December 31, 2016 in the Amsterdam Resuscitation Study (ARREST) database were analyzed. Time on scene was related to 30-day survival. RESULTS: Of the 5871 OHCA patients where resuscitation was started, 2437 did not achieve ROSC on scene. Of these, 655 patients were transported with ongoing CPR and 606 (93%) had complete rhythm data. At the moment of transport, 199 (33%) patients had a shockable rhythm, 299 (49%) pulseless electrical activity (PEA) and 108 (18%) asystole as rhythm. Twenty-nine patients (4%) were alive at 30 days. Patients who survived 30 days had a higher proportion of a shockable first monitored rhythm (89% vs. 52%, p < 0.001). Survivors had a significantly shorter time on scene (20 min vs. 26 min, p = 0.004), with the highest survival rate (8%) in patients transported within 20 min. In a multivariable model time on scene (OR 0.94; 95%CI 0.89-0.99) was independently associated with 30-day survival. CONCLUSION: In OHCA patients transported with ongoing CPR the survival rate significantly declines when time on scene increases.
BACKGROUND: In out-of-hospital cardiac arrest (OHCA), return of spontaneous circulation (ROSC) on scene occurs only in a minority of patients. The optimal duration of resuscitation on scene before transport with ongoing cardiopulmonary resuscitation (CPR) is unknown. PURPOSE: To determine the time of resuscitation on scene ('time on scene') and survival in patients transported with ongoing CPR in the Netherlands. METHODS: Data on OHCA patients (>18 years) without ROSC on scene, where resuscitation was started between January 1, 2012 and December 31, 2016 in the Amsterdam Resuscitation Study (ARREST) database were analyzed. Time on scene was related to 30-day survival. RESULTS: Of the 5871 OHCA patients where resuscitation was started, 2437 did not achieve ROSC on scene. Of these, 655 patients were transported with ongoing CPR and 606 (93%) had complete rhythm data. At the moment of transport, 199 (33%) patients had a shockable rhythm, 299 (49%) pulseless electrical activity (PEA) and 108 (18%) asystole as rhythm. Twenty-nine patients (4%) were alive at 30 days. Patients who survived 30 days had a higher proportion of a shockable first monitored rhythm (89% vs. 52%, p < 0.001). Survivors had a significantly shorter time on scene (20 min vs. 26 min, p = 0.004), with the highest survival rate (8%) in patients transported within 20 min. In a multivariable model time on scene (OR 0.94; 95%CI 0.89-0.99) was independently associated with 30-day survival. CONCLUSION: In OHCA patients transported with ongoing CPR the survival rate significantly declines when time on scene increases.
Keywords:
Advanced life support (ALS); Cardiopulmonary resuscitation (CPR); Emergency medical services (EMS); Out-of-hospital cardiac arrest (OHCA); Return of spontaneous circulation (ROSC); Rhythm at moment of transport; Survival; Time of resuscitation on scene; Transport with ongoing CPR
Authors: Jan Belohlavek; Jana Smalcova; Daniel Rob; Ondrej Franek; Ondrej Smid; Milana Pokorna; Jan Horák; Vratislav Mrazek; Tomas Kovarnik; David Zemanek; Ales Kral; Stepan Havranek; Petra Kavalkova; Lucie Kompelentova; Helena Tomková; Alan Mejstrik; Jaroslav Valasek; David Peran; Jaroslav Pekara; Jan Rulisek; Martin Balik; Michal Huptych; Jiri Jarkovsky; Jan Malik; Anna Valerianova; Frantisek Mlejnsky; Petr Kolouch; Petra Havrankova; Dan Romportl; Arnost Komarek; Ales Linhart Journal: JAMA Date: 2022-02-22 Impact factor: 157.335
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