Literature DB >> 30928396

Liposomal bupivacaine reduces opiate consumption after rotator cuff repair in a randomized controlled trial.

Paul M Sethi1, Devon T Brameier2, Nikhil K Mandava2, Seth R Miller2.   

Abstract

BACKGROUND: Arthroscopic rotator cuff repair (ARCR) provides excellent clinical outcomes but is often associated with significant postoperative pain. The use of intraoperative anesthesia in conjunction with multimodal pharmacologic strategies is a widely accepted approach for managing surgical pain and reducing opiate use. The purpose of this study was to determine whether using a combined field and suprascapular nerve block with liposomal bupivacaine (LB) in addition to an interscalene block would provide greater pain relief and a reduction in opiate consumption compared with an interscalene block alone.
METHODS: The study enrolled 50 patients with full-thickness rotator cuff tears undergoing primary ARCR surgery. Patients were randomized to receive intraoperative LB (n = 25) or not (n = 25) and given postoperative "pain journals" to document visual analog scale pain scores and to track their daily opioid consumption during the first 5 postoperative days.
RESULTS: Patients in the LB group reported statistically and clinically lower pain scores during postoperative days 1 and 2 (P < .0001 and P = .03, respectively). In addition, patients in the LB group consumed significantly fewer narcotics than the control group during the 5-day period, demonstrating a 64% reduction in total narcotic consumption (P = .002).
CONCLUSION: The findings of this study suggest that the addition of LB to multimodal anesthetic protocols significantly reduces the acute perioperative pain experienced following rotator cuff repair and the number of narcotic pills consumed in the first 5 days after ARCR. Furthermore, the findings provide guidelines for postoperative narcotic prescribing to reduce the quantity of opiates prescribed.
Copyright © 2019 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Postoperative care; analgesia; liposomal bupivacaine; opioid epidemic; pain management; rotator cuff repair

Mesh:

Substances:

Year:  2019        PMID: 30928396     DOI: 10.1016/j.jse.2019.01.008

Source DB:  PubMed          Journal:  J Shoulder Elbow Surg        ISSN: 1058-2746            Impact factor:   3.019


  9 in total

1.  Liposomal bupivacaine nerve block provides better pain control post-total shoulder arthroplasty than continuous indwelling catheter.

Authors:  Ryan Krupp; Austin Smith; John Nyland; Colton Mojesky; Deandrea Perkins; Leah Y Carreon
Journal:  Arch Orthop Trauma Surg       Date:  2022-03-02       Impact factor: 3.067

Review 2.  The role for high volume local infiltration analgesia with liposomal bupivacaine in total hip arthroplasty: A scoping review.

Authors:  Neeraj Vij; Rajesh Supra; Delena Vanvalkenburg; Nicholas Comardelle; Alan D Kaye; Omar Viswanath; Ivan Urits
Journal:  Orthop Rev (Pavia)       Date:  2022-08-05

3.  The Opioid Risk Tool: Can This Validated Tool Predict Post-Operative Opioid Dependence Following Arthroscopic Rotator Cuff Repair?

Authors:  Dennis A DeBernardis; DeBernardis Stenson; Quincy T Cheeseman; Luke S Austin
Journal:  Arch Bone Jt Surg       Date:  2022-01

4.  PROSPECT guideline for rotator cuff repair surgery: systematic review and procedure-specific postoperative pain management recommendations.

Authors:  O Toma; B Persoons; E Pogatzki-Zahn; M Van de Velde; G P Joshi
Journal:  Anaesthesia       Date:  2019-08-07       Impact factor: 6.955

5.  Surgeon-Administered Nerve Block During Rotator Cuff Repair Can Promote Recovery with Little or No Post-operative Opioid Use.

Authors:  George L Caldwell; Michael A Selepec
Journal:  HSS J       Date:  2020-01-22

6.  Network Meta-Analysis of Perioperative Analgesic Effects of Different Interventions on Postoperative Pain After Arthroscopic Shoulder Surgery Based on Randomized Controlled Trials.

Authors:  Wu Jiangping; Quan Xiaolin; Shu Han; Xiaolan Zhou; Nie Mao; Deng Zhibo; Gong Ting; Hu Shidong; Li Xiangwei; Yuan Xin; Shu Guoyin
Journal:  Front Med (Lausanne)       Date:  2022-07-08

Review 7.  Use of Opioids in the Early Postoperative Period After Arthroscopic Rotator Cuff Repair: A Systematic Review.

Authors:  William H Davis; Alexis B Sandler; John P Scanaliato; John C Dunn; Nata Parnes
Journal:  Orthop J Sports Med       Date:  2022-07-21

8.  Determining anatomic accuracy of shoulder field injection: triangular injection technique does adequately reach pain transmitters.

Authors:  Paul M Sethi; Chirag D Sheth
Journal:  JSES Int       Date:  2020-05-26

9.  Narcotic requirements after shoulder arthroplasty are low using a multimodal approach to pain.

Authors:  Paul M Sethi; Nikhil K Mandava; Nicole Liddy; Patrick J Denard; Georges Haidamous; Charles D Reimers
Journal:  JSES Int       Date:  2021-04-06
  9 in total

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