Literature DB >> 30928116

Effect of positive airway pressure therapy in children with obstructive sleep apnea syndrome: does positive airway pressure use reduce pedestrian injury risk?

Kristin T Avis1, Karen L Gamble2, David C Schwebel3.   

Abstract

INTRODUCTION: Treatment with positive airway pressure (PAP) therapy reduces injury risk among adults with obstructive sleep apnea syndrome (OSAS), but the effect of PAP therapy on children's injury risk is unknown. This study investigated whether treatment of OSAS with PAP reduces children's pedestrian injury risk in a virtual reality pedestrian environment.
METHODS: Forty-two children ages 8-16 years with OSAS were enrolled upon diagnosis by polysomnography. Children crossed a simulated street several times upon enrollment, prior to PAP treatment, and again after 3 months of PAP therapy. Children underwent sleep studies at all time points.
RESULTS: Children adherent with PAP had a significant reduction in hits by a virtual vehicle (P < .01) and less time to contact with oncoming vehicles (P < .01) following treatment. Those who were nonadherent did not show improved safety. There was no change in attention to oncoming traffic.
CONCLUSIONS: OSAS may have significant consequences on children's daytime functioning in a critical domain of personal safety: pedestrian skills. In pedestrian simulation, children with OSAS adherent to PAP therapy showed improvement in pedestrian safety and had fewer collisions with a virtual vehicle following treatment. Results highlight need for heightened awareness of the real-world benefits of treatment for pediatric sleep disorders. LEVEL OF EVIDENCE: Level II Therapeutic Study.
Copyright © 2019 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Children; Injury risk; Obstructive sleep apnea syndrome; PAP; Pedestrian safety

Mesh:

Year:  2019        PMID: 30928116      PMCID: PMC6443098          DOI: 10.1016/j.sleh.2018.12.006

Source DB:  PubMed          Journal:  Sleep Health        ISSN: 2352-7218


  37 in total

1.  Practice parameters for the medical therapy of obstructive sleep apnea.

Authors:  Timothy I Morgenthaler; Sheldon Kapen; Teofilo Lee-Chiong; Cathy Alessi; Brian Boehlecke; Terry Brown; Jack Coleman; Leah Friedman; Vishesh Kapur; Judith Owens; Jeffrey Pancer; Todd Swick
Journal:  Sleep       Date:  2006-08       Impact factor: 5.849

2.  Neuropsychological effects of pediatric obstructive sleep apnea.

Authors:  Dean W Beebe; Carolyn T Wells; Jennifer Jeffries; Barbara Chini; Maninder Kalra; Raouf Amin
Journal:  J Int Neuropsychol Soc       Date:  2004-11       Impact factor: 2.892

3.  Obstructive sleep apnea syndrome increases pedestrian injury risk in children.

Authors:  Kristin T Avis; Karen L Gamble; David C Schwebel
Journal:  J Pediatr       Date:  2014-10-25       Impact factor: 4.406

4.  Mediating factors associated with pedestrian injury in children with attention-deficit/hyperactivity disorder.

Authors:  Despina Stavrinos; Fred J Biasini; Philip R Fine; J Bart Hodgens; Snehal Khatri; Sylvie Mrug; David C Schwebel
Journal:  Pediatrics       Date:  2011-07-25       Impact factor: 7.124

5.  Influence of virtual reality training on the roadside crossing judgments of child pedestrians.

Authors:  James A Thomson; Andrew K Tolmie; Hugh C Foot; Kirstie M Whelan; Penelope Sarvary; Sheila Morrison
Journal:  J Exp Psychol Appl       Date:  2005-09

6.  Child Pedestrian Injury: A Review of Behavioral Risks and Preventive Strategies.

Authors:  David C Schwebel; Aaron L Davis; Elizabeth E O'Neal
Journal:  Am J Lifestyle Med       Date:  2011-06-17

Review 7.  The neuropsychological effects of obstructive sleep apnea: a meta-analysis of norm-referenced and case-controlled data.

Authors:  Dean W Beebe; Lisa Groesz; Carolyn Wells; Alisha Nichols; Kevin McGee
Journal:  Sleep       Date:  2003-05-01       Impact factor: 5.849

8.  Adherence to and effectiveness of positive airway pressure therapy in children with obstructive sleep apnea.

Authors:  Carole L Marcus; Gerald Rosen; Sally L Davidson Ward; Ann C Halbower; Laura Sterni; Janita Lutz; Pamela J Stading; Daisy Bolduc; Nancy Gordon
Journal:  Pediatrics       Date:  2006-03       Impact factor: 7.124

9.  Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders.

Authors:  Clete A Kushida; Michael R Littner; Max Hirshkowitz; Timothy I Morgenthaler; Cathy A Alessi; Dennis Bailey; Brian Boehlecke; Terry M Brown; Jack Coleman; Leah Friedman; Sheldon Kapen; Vishesh K Kapur; Milton Kramer; Teofilo Lee-Chiong; Judith Owens; Jeffrey P Pancer; Todd J Swick; Merrill S Wise
Journal:  Sleep       Date:  2006-03       Impact factor: 5.849

10.  Improving Positive Airway Pressure Adherence in Children.

Authors:  Michelle S King; Melissa S Xanthopoulos; Carole L Marcus
Journal:  Sleep Med Clin       Date:  2014-06-01
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  2 in total

Review 1.  Genetics and Extracellular Vesicles of Pediatrics Sleep Disordered Breathing and Epilepsy.

Authors:  Abdelnaby Khalyfa; David Sanz-Rubio
Journal:  Int J Mol Sci       Date:  2019-11-04       Impact factor: 5.923

2.  Positive airway pressure adherence in pediatric obstructive sleep apnea: A systematic scoping review.

Authors:  Alexa J Watach; Melissa S Xanthopoulos; Olufunke Afolabi-Brown; Bruno Saconi; Kathleen A Fox; Maylene Qiu; Amy M Sawyer
Journal:  Sleep Med Rev       Date:  2020-02-08       Impact factor: 11.609

  2 in total

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