Literature DB >> 30925635

Adjuvant treatment and survival in older women with triple negative breast cancer: A Surveillance, Epidemiology, and End Results analysis.

Margaret M Kozak1, Michael Xiang1, Erqi L Pollom1, Kathleen C Horst1.   

Abstract

Patients with triple negative breast cancer were identified using the Surveillance, Epidemiology, and End Results database. Competing risks analysis was used to assess the cumulative incidence of breast cancer-specific mortality (BCSM). Multivariable Fine-Gray regression was used to identify predictors of BCSM. Women age 70+ (n = 4221) were less likely to receive chemotherapy and radiation treatment (P < 0.0001) and had higher BCSM compared to younger women (P < 0.0001). There were no differences in BCSM in patients who received adjuvant treatment (P = 0.10). Stage II patients derived the greatest relative and absolute benefit from adjuvant treatment. Age was not a significant predictor of BCSM.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  breast cancer; chemotherapy; outcomes; radiation treatment; triple negative

Mesh:

Year:  2019        PMID: 30925635     DOI: 10.1111/tbj.13251

Source DB:  PubMed          Journal:  Breast J        ISSN: 1075-122X            Impact factor:   2.431


  3 in total

1.  Chemotherapy Decision-Making and Survival Outcomes in Older Women With Early Triple-Negative Breast Cancer: Evidence From Real-World Practice.

Authors:  Meng Xiu; Pin Zhang; Qing Li; Peng Yuan; Jiayu Wang; Yang Luo; Fei Ma; Ruigang Cai; Ying Fan; Qiao Li; Binghe Xu
Journal:  Front Oncol       Date:  2022-04-28       Impact factor: 5.738

2.  The impact of chemotherapy and survival prediction by machine learning in early Elderly Triple Negative Breast Cancer (eTNBC): a population based study from the SEER database.

Authors:  Kaiyan Huang; Jie Zhang; Yushuai Yu; Yuxiang Lin; Chuangui Song
Journal:  BMC Geriatr       Date:  2022-04-01       Impact factor: 3.921

3.  The Efficacy of Pegylated Liposomal Doxorubicin-Based Neoadjuvant Chemotherapy in Breast Cancer: A Retrospective Case-Control Study in Taiwan.

Authors:  Chih-Chiang Hung; Youngsen Yang; I-Chen Tsai; Chiann-Yi Hsu; Chia-Hua Liu; Jie-Ru Yang
Journal:  Biochem Res Int       Date:  2020-04-28
  3 in total

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