| Literature DB >> 30925042 |
Jessica C Stark1,2,3, Ally Huang4,5,6, Karen J Hsu7, Rachel S Dubner8, Jason Forbrook9, Suzanne Marshalla10, Faith Rodriguez11, Mechelle Washington12, Grant A Rybnicky2,3,13, Peter Q Nguyen6,14, Brenna Hasselbacher15, Ramah Jabri15, Rijha Kamran15, Veronica Koralewski15, Will Wightkin15, Thomas Martinez15, Michael C Jewett1,2,3,16,17.
Abstract
Recent advances in synthetic biology have resulted in biological technologies with the potential to reshape the way we understand and treat human disease. Educating students about the biology and ethics underpinning these technologies is critical to empower them to make informed future policy decisions regarding their use and to inspire the next generation of synthetic biologists. However, hands-on, educational activities that convey emerging synthetic biology topics can be difficult to implement due to the expensive equipment and expertise required to grow living cells. We present BioBits Health, an educational kit containing lab activities and supporting curricula for teaching antibiotic resistance mechanisms and CRISPR-Cas9 gene editing in high school classrooms. This kit links complex biological concepts to visual, fluorescent readouts in user-friendly freeze-dried cell-free reactions. BioBits Health represents a set of educational resources that promises to encourage teaching of cutting-edge, health-related synthetic biology topics in classrooms and other nonlaboratory settings.Entities:
Keywords: CRISPR-Cas9; STEM curriculum; antibiotic resistance; biological engineering education; cell-free protein synthesis; fluorescence; synthetic biology
Mesh：
Year: 2019 PMID： 30925042 DOI： 10.1021/acssynbio.8b00381
Source DB: PubMed Journal: ACS Synth Biol ISSN： 2161-5063 Impact factor: 5.110