Literature DB >> 30924472

Rational design of an improved transglucosylase for production of the rare sugar nigerose.

Jorick Franceus1, Shari Dhaene, Hannes Decadt, Judith Vandepitte, Jurgen Caroen, Johan Van der Eycken, Koen Beerens, Tom Desmet.   

Abstract

The sucrose phosphorylase from Bifidobacterium adolescentis (BaSP) can be used as a transglucosylase for the production of rare sugars. We designed variants of BaSP for the efficient synthesis of nigerose from sucrose and glucose, thereby adding to the inventory of rare sugars that can conveniently be produced from bulk sugars.

Entities:  

Year:  2019        PMID： 30924472     DOI： 10.1039/c9cc01587f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Structural Comparison of a Promiscuous and a Highly Specific Sucrose 6F-Phosphate Phosphorylase.

Authors:  Jorick Franceus; Nikolas Capra; Tom Desmet; Andy-Mark W H Thunnissen
Journal:  Int J Mol Sci       Date:  2019-08-11       Impact factor: 5.923

Review 2.  Sucrose Phosphorylase and Related Enzymes in Glycoside Hydrolase Family 13: Discovery, Application and Engineering.

Authors:  Jorick Franceus; Tom Desmet
Journal:  Int J Mol Sci       Date:  2020-04-05       Impact factor: 5.923

3.  Metabolism and Health Effects of Rare Sugars in a CACO-2/HepG2 Coculture Model.

Authors:  Amar van Laar; Charlotte Grootaert; Filip Van Nieuwerburgh; Dieter Deforce; Tom Desmet; Koen Beerens; John Van Camp
Journal:  Nutrients       Date:  2022-01-30       Impact factor: 5.717
  3 in total

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