Literature DB >> 30924426

Pre-feasibility Study for Establishing Radioisotope and Radiopharmaceutical Production Facilities in Developing Countries.

Efrain Araujo Perini1, Mikhail Skopchenko2, Tran Thu Hong3, Rahmat Harianto4, Alexis Maître5, Maidelys Rosa Rodríguez Rodríguez6, Nathalia de Oliveira Santos7, Yinglei Guo8, Xiangyu Qin9, Carlos A Zeituni1, Valeriia N Starovoitova10.   

Abstract

BACKGROUND: A significant number of developing countries have no facilities to produce medical radioisotopes and radiopharmaceuticals.
OBJECTIVE: In this paper we show that access to life-saving radioisotopes and radiopharmaceuticals and the geographical distribution of corresponding infrastructure is highly unbalanced worldwide.
METHODS: We discuss the main issues which need to be addressed in order to establish the production of radioisotopes and radiopharmaceuticals, which are especially important for developing countries as newcomers in the field. The data was gathered from several sources, including databases maintained by the International Atomic Energy Agency (IAEA), World Health Organization (WHO), and other international organizations; personal interactions with representatives in the nuclear medicine field from different regions of the world; and relevant literature.
RESULTS: Developing radioisotope and radiopharmaceutical production program and installing corresponding infrastructure requires significant investments, both man-power and financial. Support already exists to help developing countries establish their medical radioisotope production installations from several organizations, such as IAEA.
CONCLUSION: This work clearly shows that access to life-saving radioisotopes and the geographical distribution of corresponding infrastructure is highly unbalanced. Technology transfer is important as it not only immediately benefits patients, but also provides employment, economic activity and general prosperity in the region to where the technology transfer is implemented. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  IAEA; Radioisotope production; developing countries; nuclear medicine; radioisotopes in medicalzzm321990applications; radiopharmaceuticals.

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Year:  2019        PMID: 30924426     DOI: 10.2174/1874471012666190328164253

Source DB:  PubMed          Journal:  Curr Radiopharm        ISSN: 1874-4710


  2 in total

Review 1.  Production Review of Accelerator-Based Medical Isotopes.

Authors:  Yiwei Wang; Daiyuan Chen; Ricardo Dos Santos Augusto; Jixin Liang; Zhi Qin; Juntao Liu; Zhiyi Liu
Journal:  Molecules       Date:  2022-08-19       Impact factor: 4.927

2.  Addressing Global Inequities in Positron Emission Tomography-Computed Tomography (PET-CT) for Cancer Management: A Statistical Model to Guide Strategic Planning.

Authors:  Miguel Gallach; Miriam Mikhail Lette; May Abdel-Wahab; Francesco Giammarile; Olivier Pellet; Diana Paez
Journal:  Med Sci Monit       Date:  2020-08-27
  2 in total

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