Literature DB >> 30921739

Kilogram scale chemical synthesis of 2'-fucosyllactose.

Karoly Agoston1, Markus Jondelius Hederos2, Istvan Bajza2, Gyula Dekany2.   

Abstract

A scalable synthetic procedure to high quality 2'-fucosyllactose, the most abundant oligosaccharide in human breast milk, has been designed and validated in kilogram scale. The synthetic route has been developed to suit industrial environment and contains only a single chromatographic purification step.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Carbohydrates; Fucosylation; Fucosyllactose; Human milk oligosaccharides; Oligosaccharide synthesis

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Year:  2019        PMID: 30921739     DOI: 10.1016/j.carres.2019.03.006

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  1 in total

1.  Improved production of 2'-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus.

Authors:  Mingyuan Xu; Xiangfeng Meng; Weixin Zhang; Yu Shen; Weifeng Liu
Journal:  Microb Cell Fact       Date:  2021-08-23       Impact factor: 5.328

  1 in total

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